Vaccination is one of the most cost-effective ways to prevent infection. Influenza vaccines propagated in cultured cells are approved for use in humans, but their yields are often suboptimal. Here, we screened A/Puerto Rico/8/34 (PR8) virus mutant libraries to develop vaccine backbones (defined here as the six viral RNA segments not encoding haemagglutinin and neuraminidase) that support high y...

Nonhuman primates are valuable for human disease modelling, because rodents poorly recapitulate some human diseases such as Parkinson's disease and Alzheimer's disease amongst others. Here, we report for the first time, the generation of green fluorescent protein (GFP) transgenic cynomolgus monkeys by lentivirus infection. Our data show that the use of a human cytomegalovirus immediate-early en...

FARMER-DRIVEN RESEARCH ON VILLAGE CHICKEN PRODUCTION IN SANYATI, ZIMBABWE. Studies on village chicken production in Sanyati, Zimbabwe, were initiated in 1998. The objective was, in cooperation with the farmers, to find means to improve chicken production by decreasing mortality and increasing growth. The aim is that more chickens should reach slaughter weight. Thus, household consumption and in...

this study was conducted to determine the prevalence of salmonellae contamination of chicken carcasses in slaughterhouses in central iran (yazd province). 435 samples were obtained from liver, breast— before and after chilling—and bacteriological and serological examinations were done. the results showed that the rate of contamination of liver, breast meat—before and after chiller—were 8.1, 18....

objective: in recent years, antiviral drugs have been used widely in the glob to prevent and treat viral diseases. they injected into eggs to eliminate pathogens and prevent of egg transmission of disease, but the adverse effects of drugs have always been a major concern. there is little information available about the safety of antiviral drugs in the embryonated eggs of birds. the objective of...

background & aim: in this study, is done during one-year research on blue–green and green algae for antimicrobial activity in mashhad suburb. aqueous, ether, and methanol extracts from 44 species blue – green algae and green algae were examined for antimicrobial properties against four bacteria (tow positive gram bacteria and tow negative gram bacteria) and tow fungous. material & meth...

heavy metal contamination in the environment could cause harmful effects both to human health and aquatic life. numerous remediation methods had been developed to encounter with the contamination problem prior to degrade, decrease and to purify the contaminated water at minimal concentration as low as possible. therefore, in current study, commercialized chicken eggshells and hybrid akar putra ...

We quantified chicken calpain 2 (CAPN2) expression in two Chinese chicken breeds (mountainous black-bone chicken breed [MB] and a commercial meat type chicken breed [S01]) to discern the tissue and ontogenic expression pattern and its effect on muscle metabolism. Real-time quantitative PCR assay was developed for accurate measurement of the CAPN2 mRNA expression in various tissues from chickens...