Phosphatidylinositol (PtdIns) transfer proteins (PITPs) regulate signaling interfaces between lipid metabolism and membrane trafficking. Herein, we demonstrate that AtSfh1p, a member of a large and uncharacterized Arabidopsis thaliana Sec14p-nodulin domain family, is a PITP that regulates a specific stage in root hair development. AtSfh1p localizes along the root hair plasma membrane and is enr...

finger prints of 68 patients with down's syndrome and 93 controls have been collected and analyzed for topological of formulation of finger tip patterns suggested by loesch (1975). the results showed that there may be great differences in the dictionary of the finger patterns of the patients and their controls. mean lunar and radial patterns showed mostly significant differences among the patie...

background in rhinoplasty, functional and cosmetic problems of the nose are corrected. these problems cause imbalance between the nasal subunit and face. throughout these deformities, there are 4 variants, so there is a need for careful preoperative evaluation either for treatment or prevention of the occurrence. according to functional and aesthetic effects of these variables in rhinoplasty, e...

We explore theoretically the scanning tunneling microscopy of single molecules on substrates using a framework of two local probes. This framework is appropriate for studying electron flow in tip/molecule/substrate systems where a thin insulating layer between the molecule and a conducting substrate transmits electrons non-uniformly and thus confines electron transmission between the molecule a...

Novel green fluorescent protein (GFP) labeling techniques targeting specific mRNA transcripts reveal discrete phases of mRNA localization in yeast: packaging, transport, and docking. In budding yeast, ASH1 mRNA is translocated via actin and myosin to the tip of growing cells. A GFP-decorated reporter transcript containing the ASH1 3 untranslated region gRNAASH1 forms spots of fluorescence local...

This work reports on the development, and preliminary results of a multiphysics probe for deep brain monitoring of neurotransmitters and metabolites in the glioblastoma environment. We made the proof of the concept of our probe with common mice glioblastoma cells GL261 modified with Green Fluorescent Protein. A silicon probe with a platinum electrode at the tip was functionalized with an enzyme...

The syncytial cells of a filamentous fungus consist of a mass of growing, tube-like hyphae. Each extending tip is fed by a continuous flow of nuclei from the colony interior, pushed by a gradient in turgor pressure. The myco-fluidic flows of nuclei are complex and multidirectional, like traffic in a city. We map out the flows in a strain of the model filamentous fungus N. crassa that has been t...

We discuss the correct expression for the classical electrostatic energy used while analysing scanning probe microscopy (SPM) experiments if either a conducting tip or a substrate or both are used in the experiment. For this purpose a general system consisting of an arbitrary arrangement of finite metallic conductors at fixed potentials (maintained by external sources) and a distribution of poi...

Polarized cell expansion plays an important role in plant morphogenesis. Tip growth is a dramatic form of this process, which is widely used as a model to study its regulation by RAC/ROP GTPase signalling. During the dominant haploid phase of its life cycle, the moss Physcomitrella patens contains different types of cells that expand by tip growth. Physcomitrella is a highly attractive experime...