This study aims to investigate the effect of five-flavor sophora flavescens enteric-coated capsules (FSEC) on TNF-α-induced inflammatory bowel disease and its molecular mechanism. Wistar Rats were divided into 6 groups: Normal control group (group A): normal diet, drinking water; Model B): 100 μg/L TNF-α; FSEC high-dose C): 100μg/L TNF-α + (432 mg/kg); medium-dose D): (216 low-dose E): (108 Pos...

We consider the group Contc(M 2n+1, α) of Cr contactomorphisms with compact support of a contact manifold (M2n+1, α) of dimension (2n + 1) with the Cr topology. We show that the first homology group of the classifying space BContc(M 2n+1, α) for the Cr foliated M2n+1 products with compact support with transverse contact structure α is trivial for 1 ≤ r < n + (3/2). This implies that the identit...

conclusions the results indicated that there was a positive association between susceptibility to chronic hbv infection and tnf-α polymorphism. in addition, hbv patients carrying -308 gg, -857 cc, and -863 aa genotypes with lower serum levels of tnf-α had an increased risk of infection. background the host genetic background regulates the natural history of chronic hepatitis b virus (hbv) infec...

objective: different cryoprotectants are used for cryopreservation of ovarian tissue in patients at risk of infertility. ethylene glycol (eg), dimethyl sulfoxide (dmso) and propanediol (proh) have been chosen as the basic permeable cryoprotectants due to their decreased glass-formation characteristics compared to other cryoprotectants. in the present study, the effects of two different vitrific...

objective(s): increasing cytokines and reactive oxygen species (ros) during ischemia reperfusion (i-r) leads to the lung damage. adalimumab (ada) is a potent tumor necrosis factor-alpha (tnf-α) inhibitor agent. we aimed to evaluate whether ada would prevent the lung tissue from damage development over the i-r process. materials and methods:twenty seven wistar albino male rats were divided into ...

We establish the following result. Theorem. Let α : G → L(X) be a σ(X, X∗) integrable bounded group representation whose Arveson spectrum Sp(α) is scattered. Then the subspace generated by all eigenvectors of the dual representation α∗ is w∗ dense in X∗. Moreover, the σ(X, X∗) closed subalgebra Wα generated by the operators αt (t ∈ G) is semisimple. If, in addition, X does not contain any copy ...

Lipid peroxidation mediated by oxygen radical is one of the main mechanisms underlying secondary brain injury. Among all vitamin E compounds, α-tocopherol shows the most prominent antioxidative effects. It plays an important role in cell aging and injury. However, there has been no report regarding the effects of α-tocopherol on changes in brain tissue morphology after intracerebral hemorrhage ...