Properties of adenyl cyclase of normal adrenals and of a corticosterone-producing adrenal cancer of the rat have been compared. Enzyme activity was found in all particulate fractions of both tissues. The cyclase of the tumor as well as of the adrenals was stimulated by adrenocorticotropic hormone (ACTH) over similar concentration ranges. Unexpectedly, the tumor enzyme was also stimulated by epi...

Results 100 patients were included. 29% were systemic. Mean age and height were 4.26 years (0.7; 13.7) and 0.31 SD (-2.47; 5.46) respectively at disease onset, 7.1 years (1.6; 15.7) and -0.24 SD (-3.63;2.90) at onset of biologics (p<0.05), 11 years (2.3;19.5) and -0.15 SD (-4.95;3.52) at last follow-up. 93 had received anti-TNFa, 35 anti-IL1, 12 anti-IL-6 and 9 CTLA4-Ig. 45% had an active disea...

Distinct from its classic functions in the regulation of calcium and phosphorus metabolism as a systemic hormone, 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)] is involved in the local control and regulation of cellular growth and differentiation in various tissues, including epidermis (keratinocytes) and bone (osteoblasts and osteoclasts). In this review, the impact of 1alpha,25(OH)(2...

Introduction: Several factors such as diseases, medications and humoral agents can delay or speed up wound healing process. Because of the limited information about the hormonal changes during wound healing, in this study the relationship between serum levels of growth hormone, insulin and cortisol and wound healing in normal and diabetic rats was evaluated. Methods: Male Wistar rats )weigh...

In order to investigate the effect of seed pretreatment with growth regulators on biochemical characteristics of red bean genotypes, a factorial experiment was carried out in a randomized complete block design with three replications. In this research, seed pretreatment with growth regulators namely salicylic acid (SA) and naphthalene acetic acid (NAA) were applied at four levels including P0: ...