Tuberculosis incidence among aborigines is significantly higher than for Han Chinese in Taiwan, but the extent to which Mycobacterium tuberculosis (MTB) strain characteristics contribute to this difference is not well understood. MTB isolates from aborigines and Han Chinese living in eastern and southern Taiwan, the major regions of aborigines, were analyzed by spoligotyping and 24-loci MIRU-VN...

The distribution of 20 variable regions resulting from insertion-deletion events in the genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium canettii, Mycobacterium microti, and Mycobacterium bovis. This approach showed that the majority of these polymorphisms did not occur independently in the differe...

OBJECTIVE The aim of this study was to use spoligotyping and large sequence polymorphism (LSP) to study the population structure of M. tuberculosis complex (MTBC) isolates. METHODS MTBC isolates were identified using standard biochemical procedures, IS6110 PCR, and large sequence polymorphisms. Isolates were further typed using spoligotyping, and the phenotypic drug susceptibility patterns we...

Molecular epidemiology has revealed that Mycobacterium tuberculosis (Mtb), formerly regarded as highly conserved species, displays a considerable degree of genetic variability that can influence the outcome of the disease as well as the innate and adaptive immune response. Recent studies have demonstrated that Mtb families found worldwide today differ in pathology, transmissibility, virulence, ...

INRODUCTION MARTINUS VAN MARUM was born in Delft, Holland, and graduated in medicine and botany in Groningen in 1773. He moved to Haarlem, where in 1777 he was appointed Director of the 'Cabinet of Natural Curiosities' of the Hollandsche Maatschappij der Wetenschappen,2 and in 1794 he became the second secretary of this society. In 1784 he also became the Librarian of the Teyler Stichting, and ...

the family can play an important role in the prevention of suicide if it is capable of aiding the mental health care services in the early detection and management of family members at risk. in order to attain that goal the whole family should be qualified and rid of some myths associated with suicidal behavior. some scientific criteria which should be taken into consideration by the family in ...

abstract aim and background: establishing and maintaining family and prevention of family breakdown involves having certain abilities and skills. the aim of the present study was to evaluate the role of different dimensions of spirituality and forgiveness as predictors of family efficacy. methods and materials: a correlational method was employed and the following measures were administered to ...

The purpose of this study was to provide information about the genetic diversity and prevalent genotype of Mycobacterium tuberculosis in a low-endemic setting in northwestern state of Paraná in Southern Brazil. We employed spoligotyping and mycobacterial interspersed repetitive units-variable number tandem repeat (MIRU-VNTR) techniques to genotype M. tuberculos isisolates from patients with pul...