A study of reconstructive operations for ischaemia of the legs showed a correlation between a high preoperative haemoglobin level and early postoperative reocclusion. The mean preoperative haemoglobin level of patients with early reocclusion (165 +/- 3 g/l, SEM) was significantly higher (p less than 0.001) than that of patients who did not reocclude (153 +/- 3 g/l). There was no significant dif...

High performance liquid chromatography (HPLC) is increasingly being used to estimate variant haemoglobins. A case of haemoglobin S/D (HbS/D) is presented, which was misdiagnosed as haemoglobin S/E (HbS/E) by HPLC. The patient was a 22 year old woman with sickle cell anaemia. Subsequent haemodilution by blood transfusion clearly elucidated the haemoglobin D peak on HPLC. Sample dilution experime...

High performance liquid chromatography (HPLC) is increasingly being used to estimate variant haemoglobins. A case of haemoglobin S/D (HbS/D) is presented, which was misdiagnosed as haemoglobin S/E (HbS/E) by HPLC. The patient was a 22 year old woman with sickle cell anaemia. Subsequent haemodilution by blood transfusion clearly elucidated the haemoglobin D peak on HPLC. Sample dilution experime...

A Ghanaian family is described in which a sickle-cell haemoglobin C man married to a sickle-cell thalassaemia woman produced 12 children (eight alive). Four children have sickle-cell anaemia, two sickle-cell haemoglobin C disease, one has sickle-cell thalassaemia, and one is asymptomatic haemoglobin C thalassaemia.It is emphasized that the contribution that adult sickle-cell disease patients ma...

Haemolytic crisis in glucose-6-phosphate dehydrogenase deficient individuals following topical application of henna occurred in four children: a female neonate (haemoglobin 50 g/l, serum bilirubin 700 micromol/l), who recovered after exchange transfusion; a male infant (haemoglobin 28 g/l) who died despite transfusion; and two preschool children (haemoglobin 40 and 41 g/l respectively).

A woman was screened for diabetes using glycated haemoglobin (HbA1c). Vastly different results were obtained by high performance liquid chromatography (45%), immunoassay (2.9%), and affinity chromatography (4.2%) compared with the non-diabetic range of less than 6.4%. Mass spectral studies confirmed the presence a haemoglobin variant, haemoglobin Marseille-Long Island which had confounded inter...

BackgroundThe optimum transfusion strategy in patients with fractured neck of femur is uncertain, particularly if there coexisting cardiovascular disease.MethodsWe conducted a prospective, single-centre, randomised feasibility trial two strategies. We randomly assigned undergoing surgery for to restrictive (haemoglobin, 70–90 g L−1) or liberal 90–110 throughout their hospitalisation. Feasibilit...

Background & aim: Low levels of maternal haemoglobin and haematocrit in the first, second, and third trimesters are considered as possible risk factors regarding low birth weight (LBW) and preterm labour (PTL). The present study aimed to evaluate the relationship between maternal haemoglobin (Hb) and haematocrit (HCT) levels with LBW and PTL. Methods: This cross-sectional study was conducted on...

This study was conducted to determine the prevalence and effect of parasitic infection on erythrocyte indices in trade camels slaughtered in Maiduguri, Nigeria. Two hundred adult one humped camels comprised of 87 (43.5 %) males and 113 (56.5 %) females were examined for helminths and hemoparasites at their slaughter time according to the standard procedures. An overall prevalence of 79 % for s...