purpose: to report three cases of alport syndrome in one  family with anterior lenticonus and retinal flecks. patients and findings: three members of one family with consanguineous parents are presented who had renal and ocular involvement. they had anterior lenticonus and a beaten bronze appearance in the macula. reduced visual acuity and photophobia were the chief complaints of these patients...

Background: Palliative whole brain radiotherapy (WBRT) has been the standard treatment for brain metastases. Ionizing radiation is known to be one of the most potent cataractogenic agents. We aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (OAR) in patients with brain metastasis who undergone WBRT. Materials and Methods: Ten conse...

The eye lens consists of a layer of epithelial cells that overlay a series of differentiating fiber cells that upon maturation lose their mitochondria, nuclei and other organelles. Lens transparency relies on the metabolic function of mitochondria contained in the lens epithelial cells and in the immature fiber cells and the programmed degradation of mitochondria and other organelles occurring ...

Leiomyoma is a rare benign neoplasm deriving from smooth muscle. Vascular leiomyoma is its most common subtype in the oral cavity. It may appear at any age with the greatest incidence in the 4th and 5th decade of life. The common manifestation is a slow-growing, asymptomatic, submucousal mass. The diagnosis is only through microscopic examination requiring special staining...

Introduction: Dental panoramic radiography (DPR) is one of the most frequent diagnostic X-ray procedures, the application of which is currently on a growing trend. During DPR, several radiosensitive tissues, such as the lens of the eyes, parotid gland, and thyroid gland, contribute to the radiation field, and it is necessary to monitor their received dose. The aim of t...

Objective(s) Extracellular matrix (ECM) and basement membrane (BM) play important roles in many developmental processes during development and after birth. Among the components of the BM, collagen fibers specially type IV are the most important parts. The aim of this study was to determine the time when collagen type IV appears in the BM of lens structure during mouse embryonic development. M...