Microcomputerized tomography (micro-CT) allows discriminating very smal lchanges in dental hard tissue volumes. The aim of the present study was to create a new method for obtaining high-resolution, three-dimensional images of dental hard tissue development using micro-CT, and to observe the changes in dental hard tissue development and composition in growing rat pups. Tooth germs from rats at ...

The authors present five cases of combined oral mucosa-mandible defects reconstructed with the vascularized internal oblique-iliac crest myoosseous free flap. This technique has many advantages compared to other conventional methods such as the radial flap, scapula flap, and fibula flap. Vascularized iliac crest flaps provide sufficient high-quality bone suitable for reconstructing segmental ma...

INTRODUCTION: There is significant demand for orthopaedic implants that are both bioactive and exhibit material properties that are compatible to those of native and healthy tissue [1]. Synthetic materials play an important role in bone repair and bone replacement. In the case of poly (L-lactide) (PLLA), one of the main problems is slow degradation, which further spark tissue loss due to revisi...

Successful treatment strategies for cardiovascular diseases have often been initiated and driven by surgeons, which is true for both coronary artery and valvular heart diseases. Radical excision of diseased tissue, repair and replacement strategies lead to long-term successful treatment of the underlying diseases and clearly improved patient outcome. For many surgeons it was and may still be ha...

Figure Legend: Figure 1 Bone Fibrous osteodystrophy in a male F344/N rat from a chronic study. There is replacement of bone by fibrous connective tissue. Figure 2 Bone Fibrous osteodystrophy in a male F344/N rat from a chronic study (same animal as in Figure 1). There is replacement of cortical bone by fibrous connective tissue. Figure 3 Bone Fibrous osteodystrophy in a male F344/N rat from a c...

Abstract The world of biomaterials has been continuously evolving. Where in the past only mono-material implants were used, growth technology and collaboration between researchers from different sectors led to a tremendous improvement implant industry. Nowadays, composite materials are one leading research areas for biomedical applications. When we look toward hard tissue applications, metal-ba...