background and objective: although hepatitis b vaccine immunogenicity is high, certain risk factors such as age, tobacco consumption, obesity and genetic background have been associated with low responsiveness to hbv vaccine. we aimed to evaluate the role of occult hepatitis b virus (hbv) infection in non-responder adults to hbv vaccine in a low endemic area for hbv. material and methods : a to...

Background and Aims: HDV is a defective satellite virus and classified in genus Deltavirus. Its disease is related and limited to HBV-infected patients. Acute infection of delta agent occurs in two different patterns simultaneous infection with both HBV & HDV or super infection of chronically HBV infected patients that lead to more sever type of hepatitis. According to genetic diversity of geno...

Background and aims: Hepatitis B virus (HBV) is one of the important public health diseases in Iran.Therefore, to control the prevalence of the disease, knowledge is required regarding the risk factor ofHBV. Accordingly, the aim of this study was to determine the risk factors of HB transmission.Methods: A retrospective case-control study was conducted on the possible risk fact...

background hepatitis b virus (hbv) is one of the most common chronic viral infections in the world. iran has a low to intermediate hbv prevalence and approximately 1.5 million people are living with hbv infection. the impact of hbv in iran is unknown and given the very low levels of alcohol consumption, this region provides an opportunity to examine the impact of isolated chronic hbv infection....

background: the household transmission of hepatitis b virus (hbv) is a major health problem. high incidence of hbv infection is observed within the household contacts of hbv carriers. we aimed to evaluate serological markers of hepatitis b infection among family members of hbv carriers in arak, central iran. methods: data were collected from the 100 chronic hbv carriers (subjects with positive ...

childhood hepatitis b virus (hbv) infection causes both medical and public health challenges. infants who acquire hbv parentally have up to 90% risk of developing chronic hbv infection. it is now estimated that approximately 10% of worldwide cancers are attributable to viral infection, with the vast majority (>85 %) occurring in the developing world. in this distribution, elevated rate and prev...

conclusions in conclusion, the prevalence of hbv infection was low in the south of iran, but genotype d represented the major hbv genotype in this population. among the variables, age, duration of hd, history of blood transfusion, and using shared hd devices influenced the prevalence of hbv among hd patients. results both kinds of assay determined that nine (5.88%) patients were hbv positive (h...

The gut microbiota in the hepatitis B virus related acute-on-chronic liver failure (HBV-ACLF) is poorly defined. We aim to uncover characteristics of HBV-ACLF and other HBV associated pathologies. analyzed microbiome patients with or pathologies healthy individuals by 16S rRNA sequencing metagenomic fecal samples. 212 HBV-ACLF, 252 chronic (CHB), 162 HBV-associated cirrhosis (HBV-LC) 877 were r...

Background: Torque teno virus (TTV) was the first human Anelloviridae detected in a Japanese patient with an unknown type of hepatitis in 1997. TTV is by far the first known single-stranded circular DNA virus infecting human. In spite of its widespread nature in human population, its pathogenesis is still unclear. In addition, information regarding TTV infection in Iranian population is limited...