Head and neck cancers are a diverse group of malignancies that includes an increasing number of virally mediated cancers in addition to tumors caused by tobacco and alcohol use. In both cases, tumor development is intimately related to the host immune system, and the status of an endogenous antitumor response is likely prognostic. Virally mediated cancers provide unique targets for preventive v...

Head and neck cancer is the 5th most common cancer in the world with half a million new cases reported globally every year, 44,600 within the United States. Up to 40% of head and neck cancer patients will eventually die because of it. With half of patients having an advanced stage of disease upon initial diagnosis. Squamous cell carcinoma contributes to 95% of head and neck cancers. Squamous ce...

Background: Nowadays, radiotherapy is used effectively for treatment of head and neck cancers. Mucositis is one of the most important side effects of radiotherapy. Radio-protective agents protect tissues and cells against the adverse effects due to ionizing radiation and cleave radiation-induced free radicals. Lycopene as a potent antioxidant protects cells against oxidative damage by free radi...

Introduction: Hypothyroidism is one of the frequent side effects of radiotherapy of head and neck cancers, breast cancer, and Hodgkin's lymphoma. It is recommended to estimate the normal tissue complication probability of thyroid gland using radiobiological modeling during treatment planning. Moreover, the use of artificial neural network is also proposed as a new method for t...

Background: This research was conducted to evaluate the potential benefits of zinc sulphate in the prevention of radiation induced mucositis in patients who are being treated for head and neck cancers. Materials and Methods: Forty patients with proven cancers of head and neck were randomly divided into 2 equal groups that either received zinc sulphate or placebo (control group). Patients who re...

Introduction: Acute Lymphoblastic Leukemia (ALL) and Non Hodgkin’s Lymphoma(NHL) are the most common cancers in childhood and  adolescence. Most children with ALL and NHL have long term survival (>80%). Endocrinopathy is a common complication in pediatric cancers following the treatment (20-50% prevalence), in addition, cytotoxic chemotherapy and radiotherapy can influence side effect on growt...

BACKGROUND Published studies suggesting a relationship between vitamin D and some common cancers sparked interest in the association of vitamin D with head and neck cancers. Prolonged darker months in Finland are associated with lower levels of ultraviolet B radiation, raising concerns about low vitamin D levels. METHODS We used a nested case--control study in the prospective Alpha-Tocopherol...

Introduction: Synovial sarcoma makes up 8–10% of all soft tissue sarcomas, and constitutes 3–10% of all sarcomas occurring in the head and neck region. It shows male predominance (3:2), and the mean age of presentation is 30 years.   Case Report: A 51-year-old gentleman presented with right-sided neck swelling which had been progressively increasing in size for the past 2 years. A computed ...