نتایج جستجو برای: heart contractility
تعداد نتایج: 396124 فیلتر نتایج به سال:
Cardiac remodeling during heart failure development induces a significant increase in the activity of the L-type Ca(2+) channel (Cav1.2). However, the effects of enhanced Cav1.2 activity on myocyte excitation-contraction (E-C) coupling, cardiac contractility, and its regulation by the beta-adrenergic system are not clear. To recapitulate the increased Cav1.2 activity, a double transgenic (DTG) ...
It is unclear whether preceding repetitive brief ischemia causes any improvement in the energy efficiency of intracellular calcium cycling or crossbridge cycling that may lead to cardioprotection after subsequent sustained ischemia/reperfusion, a phenomenon called ischemic preconditioning. To address this issue, left ventricular (LV) contractility (E(max)) and the relation between myocardial ox...
Digitalis is a genus of about 20 species of herbaceous perennials, shrubsand biennials commonly called foxgloves. The term digitalis is also used for drug preparations that contain cardiac glycosides, particularly the one called Digoxin, extracted from various plants of this genus. Cardiac glycosides cause arteriolar and venous constriction in a variety of mammalian species including human bein...
Abstract Background There are a lot of reports the renal failure and heart due to coarctation aorta. However, there no case in which revascularization dramatically improved left ventricular function patients with progressive decline function. Herein, we present rare was by surgical treatment for dysfunction atypical Case presentation A 58-year-old man underwent axillary artery-bilateral femoral...
Hypertrophic cardiomyopathy (HCM) is an inherited disease of the heart muscle characterized by otherwise unexplained thickening of the left ventricle. Left ventricular outflow tract (LVOT) obstruction is present in approximately two-thirds of patients and substantially increases the risk of disease complications. Invasive treatment with septal myectomy or alcohol septal ablation can improve sym...
AIMS The factors responsible for cardiomyopathy are not fully understood. Our studies of the transcriptome of human embryonic stem cell-derived cardiomyocytes identified novel genes up-regulated during cardiac differentiation, including RBM24. We therefore studied how its deficiency affected heart development. METHODS AND RESULTS The expression of Rbm24 was detected in mouse cardiomyocytes an...
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