UNLABELLED Recent efforts in our laboratory have explored the use of polyacrylate nanoparticles in aqueous media as stable emulsions for potential applications in treating drug-resistant bacterial infections. These emulsions are made by emulsion polymerization of acrylated antibiotic compounds in a mixture of butyl acrylate and styrene (7:3 wt/wt) using sodium dodecyl sulfate as a surfactant. P...

background: emulsions are thermodynamically unstable systems that can be kinetically stable by adding substances known as emulsifiers and/or thickening agents. by respect to the functional properties of gum tragacanth (gt), and its breakage probability during irradiation treatment, the major aim of this study was to investigate the stability of oil in water emulsion in the presence of different...

Antioxidant potential of the fungal dye, produced by a strain selected from the collection of Epicoccum nigrum bioresearch platform (acronym MIUG) was partially characterized in previous studies. However, the fungal dye antioxidant capacity compared with other potential colorant inhibitors of lipid peroxidation (e.g. cochineal dye) has not been fully elucidated, especially regarding its behavio...

Hagfish slime is an ultra dilute, elastic and cohesive hydrogel that deploys within milliseconds in cold seawater from a glandularly secreted exudate. The slime is made of long keratin-like fibers and mucin-like glycoproteins that span a network which entraps water and acts as a defense mechanism against predators. Unlike other hydrogels, the slime only confines water physically and is very sus...

BACKGROUND Adjuvant formulations are critical components of modern vaccines based on recombinant proteins, which are often poorly immunogenic without additional immune stimulants. Oil-in-water emulsions comprise an advanced class of vaccine adjuvants that are components of approved seasonal and pandemic influenza vaccines. However, few reports have been published that systematically evaluate th...

The purpose of the present study was to develop a formulation of recombinant hepatitis B vaccine with improved stability at elevated temperatures. A validated in vitro antigen reactivity assay was used to measure the stability of the vaccine. The formulation development focused on modification of the interactions between the antigen and aluminum hydroxide adjuvant and subsequent optimization of...

Emulsions have long been utilized to make materials for foods, drugs, cosmetics, and displays because of their efficient encapsulation properties. While they are most commonly made in bulk, recent advances in microfluidics have enabled the design and manipulation of emulsion drops with unprecedented control and flexibility, albeit only on a drop-bydrop basis. Multiple-phase emulsions of very hi...

This paper analyzes stability and convergence properties of a conjugate heat transfer problem in one space dimension. The energy method is used to derive boundary and interface conditions and to prove that the semi-discrete problem is stable. The numerical scheme is implemented using 2nd-, 3rdand 4th-order finite difference operators on Summation-By-Parts (SBP) form. The boundary and interface ...