introduction: the aim of this study was to investigate the effect of the hsp-70 (heat shock protein-70) induction in the lysate of heat shocked tumor cells on splenocyte proliferation, nitric oxide production by peritoneal macrophages, and fibrosarcoma tumor size reduction in balb/c mice. material and methods: wehi 164 cells (mouse fibrosarcoma cell line) were injected subcutaneously into the r...

Chinese hamster ovary cells exposed to the sulfhydryl compound cysteamine combined with heat treatment at 44 degrees C developed thermotolerance within 8 h. After initial treatment either with 15 min cysteamine (0.4 mM) at 37 degrees C immediately followed by 15 min heat at 44 degrees C or with 15 min cysteamine (0.4 mM) at 44 degrees C, the magnitude of thermotolerance developed was identical....

Carbonitriding of four types of steels, namely, low carbon steel (LCS), medium carbon steel (MCS), low alloy steel (LAS) and high alloy steel (HAS) was achieved using cyanide salt bath heat treatment process. The steels, after preheating, were heated in a diesel fired salt bath heat treatment furnace and then quickly quenched in different media including air, oil and brine. The heat treatment p...

Heat treatment is often used to improve the dimensional stability of wood. In this study, the effects of heat treatment on the physical properties and surface roughness of Turkish Hazel (Corylus colurna L.) wood were examined. Samples obtained from Kastamonu Forest Enterprises, Turkey, were subjected to heat treatment at varying temperatures and for different durations. The physical properties ...

Abstract Local tumour hyperthermia for cancer treatment is currently used either for ablation purposes as an alternative to surgery or less frequently, in combination with chemotherapy and/or radiation therapy to enhance the effects of those traditional therapies. As it has become apparent that activating the immune system is crucial to successfully treat metastatic cancer, the potential of boo...

Induction of WAF1 expression was investigated after heat treatment (44 degrees C, 30 min) in two human glioblastoma cell lines with the wild-type or a mutant p53 gene. WAF1 accumulation was induced by heat treatment in A-172 cells carrying the wild-type p53 gene but not in T98G cells carrying the mutant p53 gene. We examined whether this phenomenon was due to the induction of WAF1 expression. N...

Acer rubrum L., A. saccharum Marsh., Quercus alba L. and Q. rubra L. seedlings subjected to soil and stem base heat treatments showed rapid declines in rates of transpiration and photosynthesis. Reductions in photosynthetic rate were partly attributable to mesophyll inhibition. Quercus seedlings were less able to maintain transpiration and photosynthesis after heat treatment than Acer seedlings...

Cells may sense heat shock via the accumulation of thermally misfolded proteins. To explore this possibility, we determined the effect of protein misfolding on gene expression in the absence of temperature changes. The imino acid analog azetidine-2-carboxylic acid (AZC) is incorporated into protein competitively with proline and causes reduced thermal stability or misfolding. We found that addi...

Hyperthermia (HT) has shown promising antitumor effects against various types of malignant tumors, and its pleiotropic effects support its combined use with radiotherapy and/or chemotherapy. However, HT is rendered less effective by the acquisition of thermoresistance in tumors, which arises through the elevation of heat shock proteins (HSPs) or other tumor responses. In mammals, the induction ...