نتایج جستجو برای: hek 293 cells

تعداد نتایج: 1389104  

Journal: :Cellular signalling 2014
Peiying Yu Min Sun Van Anthony M Villar Yanrong Zhang Edward J Weinman Robin A Felder Pedro A Jose

Dopamine D1-like receptors (D1R and D5R) stimulate adenylyl cyclase (AC) activity, whereas the D2-like receptors (D2, D3 and D4) inhibit AC activity. D1R, but not the D5R, has been reported to regulate AC activity in lipid rafts (LRs). We tested the hypothesis that D1R and D5R differentially regulate AC activity in LRs using human embryonic kidney (HEK) 293 cells heterologously expressing human...

Journal: :Molecular pharmacology 2006
Agnes C L Martin Dermot M F Cooper

Although the molecular identity of capacitative Ca(2+) entry (CCE) channels remains elusive, transient receptor potential channel (TRPC) family members 3, 6, and 7, which are activated by diacylglycerol (DAG), have been put forward as possible candidates. Because human embryonic kidney (HEK) 293 cells endogenously express these TRP subunits, this cell line is suitable for investigating whether ...

Journal: :The Biochemical journal 2007
Gunther Marsche Sasa Frank John G Raynes Karen F Kozarsky Wolfgang Sattler Ernst Malle

During the acute-phase reaction, SAA (serum amyloid A) replaces apoA-I (apolipoprotein A-I) as the major HDL (high-density lipoprotein)-associated apolipoprotein. A remarkable portion of SAA exists in a lipid-free/lipid-poor form and promotes ABCA1 (ATP-binding cassette transporter A1)-dependent cellular cholesterol efflux. In contrast with lipid-free apoA-I and apoE, lipid-free SAA was recentl...

1999
VINZENZ M. STEPAN DIETER F. KRAMETTER MASASHI MATSUSHIMA ANDREA TODISCO JOHN DELVALLE Dieter F. Krametter Masashi Matsushima Andrea Todisco John Delvalle

Stepan, Vinzenz M., Dieter F. Krametter, Masashi Matsushima, Andrea Todisco, John Delvalle, and Chris J. Dickinson. Glycine-extended gastrin regulates HEK cell growth. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R572–R581, 1999.—Posttranslational processing of progastrin to a carboxy terminally amidated form (G-NH2) is essential for its effect on gastric acid secretion and o...

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