background: controlling the hemodynamic situation of patients who have spinal operation is of prime importance, and maintaining the heart rate and blood pressure in normal or low- normal levels in these patients can reduce their bleeding loss. one of the commonly used drugs for this purpose is remifentanil. another sedative-hypnotic-analgesic drug, with acceptable effects is dexmedetomidine. th...

After myocardial infarction (MI), the left ventricle (LV) undergoes ventricular remodeling characterized by progressive global dilation, infarct expansion, and compensatory hypertrophy of the noninfarcted myocardium. Little attention has been given to the response of remodeling myocardium to additional hemodynamic overload. Studies have indicated that gender may influence remodeling and the res...

Simultaneous implementation of magnetic resonance imaging methods for Arterial Spin Labeling (ASL) and Blood Oxygenation Level Dependent (BOLD) imaging makes it possible to quantitatively measure the changes in cerebral blood flow (CBF) and cerebral oxygen metabolism (CMRO(2)) that occur in response to neural stimuli. To date, however, the range of neural stimuli amenable to quantitative analys...

The receptors mediating the hemodynamic responses to cannabinoids are not clearly defined due to the multifarious pharmacology of many commonly used cannabinoid ligands. While both CB1 and TRPV1 receptors are implicated, G protein-coupled receptor 55 (GPR55) may also mediate some of the hemodynamic effects of several atypical cannabinoid ligands. The present studies attempted to unravel the pha...

Brain activity can be monitored non-invasively by near-infrared spectroscopy (NIRS), which has several advantages in comparison with other imaging methods, such as flexibility, portability, low cost and biochemical specificity. Moreover, patients and children can be repetitively examined. Therefore, the objective of the study was to test the feasibility of NIRS for the event-related approach in...

To identify the mechanisms that couple hemodynamic stress to alterations in cardiac gene expression, DNA constructs containing the rat B-type natriuretic peptide (BNP) promoter were injected into the myocardium of rats, which underwent bilateral nephrectomy or were sham-operated. Ventricular BNP mRNA levels were induced about 4-fold; and the BNP reporter construct containing the proximal 2200 b...

In the practical conduct of Anaesthesia, Airway management is crucial to outcome & best patient care. A total n=114 patients,30-50 yrs with mean age 38.736± 4.36 years; 57 each group Laryngoscopy and ETT; LMA undergoing elective surgery 30 minutes 01-hour duration in controlled hypertensives were included study. The hemodynamic response was noted, recording pulse rate, Systolic BP, Diastoli...

CONTEXT Loosening of associations has long been considered a core feature of schizophrenia, but its neural correlate remains poorly understood. OBJECTIVE To test the hypothesis that, in comparison with healthy control subjects, patients with schizophrenia show increased neural activity within inferior prefrontal and temporal cortices in response to directly and indirectly semantically related...

This study examines single trial hemodynamic response estimation in event-related fNIR spectroscopy. In a working memory task, the estimates of single trial hemodynamic responses in dorsolateral prefrontal cortex are compared across subjects. ©2003 Optical Society of America OCIS codes: (300.6340) Spectroscopy, infrared; (070.0070) Fourier optics and optical signal processing