Introduction: In recent work we showed that by means of sparse estimation techniques the spatial and temporal evolution of single-trial BOLD responses can be automatically detected without any prior knowledge of the stimulus timing and without thresholding: paradigm free mapping (PFM) [1]. However, fMRI time series also contain physiological and instrumental fluctuations which can hinder the de...

In functional magnetic resonance imaging (fMRI), modeling the complex link between neuronal activity and its hemodynamic response via the neurovascular coupling requires an elaborate and sensitive response model. Methods based on physiologic assumptions as well as direct, descriptive models have been proposed. The focus of this study is placed on such a direct approach that allows for a robust ...

Al-Hussaini and Ateya [3−4] obtained the maximum likelihood and Bayes estimates of the parameters, reliability function (rf) and hazard rate function (hrf) of a mixture of two components of truncated type I generalized logistic distribution, TTIGL(β, γ, α), with location parameter β, scale parameter γ and shape parameter α, when the location parameters are equal to zero, when the scale paramete...

Submit Manuscript | http://medcraveonline.com techniques for building meaningful models. More recently, seve­ ral methods of introducing one or more parameters to generate new distributions have been proposed. Among these methods, the compounding of some discrete and important lifetime distributions has been in the vanguard of lifetime modeling. So, several families of distributions were invest...

Submit Manuscript | http://medcraveonline.com techniques for building meaningful models. More recently, seve­ ral methods of introducing one or more parameters to generate new distributions have been proposed. Among these methods, the compounding of some discrete and important lifetime distributions has been in the vanguard of lifetime modeling. So, several families of distributions were invest...

BACKGROUND The International Classification of Functioning (ICF) has acquired a central role in the WHO Family of International Classifications and it has been extensively adopted as the reference framework for health-related functioning (HrF). This review aims to provide a description of the ICF/HrF to contextualise ICF/HrF in relation to other approaches to health functioning and to describe ...

Erythrocytes are poorly lysed by homologous complement, whereas they are readily lysed by heterologous complement. This phenomenon had been attributed to an interference by the cell surface with the action of complement components C8 and C9. To isolate the responsible membrane constituent, detergent-solubilized human erythrocyte (EH) membranes were subjected to affinity chromatography by using ...

BACKGROUND Hypoxemia is associated with worse outcomes in COPD. The aim of the study was to investigate the prevalence, incidence, and risk factors of hypoxic respiratory failure (HRF) in COPD. PATIENTS AND METHODS This was a longitudinal analysis of data from the Swedish National Register of COPD. HRF was defined as resting saturation ≤88% or long-term oxygen therapy. Risk factors for develo...