In studies that use electronic health record data, imputation of important data elements such as Glycated hemoglobin (A1c) has become common. However, few studies have systematically examined the validity of various imputation strategies for missing A1c values. We derived a complete dataset using an incident diabetes population that has no missing values in A1c, fasting and random plasma glucos...

ABSTRACT: Objective: To evaluate the association between dental visits and variation in glycated hemoglobin index (A1C) of patients with type 2 diabetes (T2DM) well or not glycemic control over time. Methods: Patients T2DM, A1C ≥ 7% (not well-controlled) < (well-controlled), who attended a primary care service were followed up from January 2010 to May 2018. The outcome was obtained reference...

BACKGROUND Annual hemoglobin A1c testing is recommended for patients with diabetes mellitus. However, it is unknown how consistently patients with diabetes mellitus receive hemoglobin A1c testing over time, or whether testing consistency is associated with adverse cardiovascular outcomes. METHODS AND RESULTS We identified 1 574 415 Medicare patients (2002-2012) with diabetes mellitus over the...

BACKGROUND Sleep-disordered breathing (SDB) is a prevalent condition associated with significant comorbidities, including hypertension, obesity, cardiovascular disease, and insulin resistance. It has been previously shown that the severity of insulin resistance is related to the severity of SDB. METHODS Using a 72-hour continuous glucose monitoring system, we studied changes in interstitial g...

Measurement of hemoglobin A1c (Hb A1c) 2 is a fundamental component of the management of patients with diabetes mellitus. Hb A1c measurement provides an indication of chronic exposure to glucose and is extensively used for both monitoring long-term glycemic status and evaluating whether an individual patient has attained adequate metabolic control. The patient’s Hb A1c value is used by clinicia...

OBJECTIVE We have already reported that A1C is elevated because of iron deficiency in late pregnancy among nondiabetic pregnant women. This report examined whether the same phenomenon is observed in pregnant women with diabetes. RESEARCH DESIGN AND METHODS This longitudinal study was conducted in 17 pregnant women with diabetes (20-35 weeks of pregnancy). A1C, serum glycated albumin, erythrocyt...