The sensitivity of anuran to the effects habitat destruction and contamination has led a preoccupying global decline in their populations. Morphological biomarkers such as micronuclei other erythrocyte nuclear abnormalities (ENAs), well occurrence hepatic melanin, can be used evaluate impacts. In present study, these two parameters were combined for situ assessment soybean cultivation on grassf...

cell free dna (cfdna) is a genetic biomarker that is present in serum or plasma in high concentration in many types of cancer. identification of circu-lating cancer related dna molecules in serum or plasma is a non-invasive tool for early diagnosis and prognosis in many cancer patients. for this review, study selection and data extraction were performed by the authors. detection of point mutati...

rodlet cells are frequently found in teleost fishes and although their role in organisms is not completely understood. the occurrence of these cells are related to stress and may undergo changes in contaminated environments, thereby allowing their use as biomarkers. this hypothesis is tested in the present study. thirty specimens of oreochromis niloticus were divided into three groups, two grou...

introduction: serum c-reactive protein (crp) is believed to be increased in metastatic urothelial cancer of the bladder. however, the changes depend on the stage and grade of the upper tract urothelial carcinoma (utuc). this study aimed to compare low-range and high-range serum crp and haptoglobin in new cases of utuc. materials and methods: blood was collected from newly diagnosed patients wit...

Hepatic fibrosis is an effusive wound healing process, characterized by an excessive deposition of extracellular matrix (ECM), as the consequence of chronic liver injury of any etiology. Current therapeutic repertoire for hepatic fibrosis is limited to withdrawal of the noxious agent, which is not always feasible. Hence, in this article, the antifibrotic effects and possible mechanisms of r-sHS...