The presence of hepatitis B surface (HBsAg) and core (HBcAg) antigens was investigated by immunofluorescence in specimens of liver tissue obtained at necrospy in 107 patients with primary hepatic carcinoma. HBsAg was detected in the cytoplasm of liver cells in 16 cases, and in eight of them the antigen was also found in malignant cells. HBcAg, which was present in the nuclei of liver cells in e...

Background: Hepatitis B virus infection is a worldwide health problem. Vertical transmission is a route of Hepatitis B virus infection that is regarded as a considerable factor in Hepatitis B virus prevention program all over the world. Objective: This study was conducted to screen the hepatitis B surface antigen, hepatitis B surface antibody and hepatitis B e antigen in pregnant women. Methods...

It has been shown that (+)-cyanidanol-3, therapeutically administered during the course of acute hepatitis B, is able to favor the elimination of hepatitis B surface antigen (HBsAg) from the blood. This observation suggests that (+)-cyanidanol-3 might stimulate the cell-mediated immune response, since it is known that this type of response is responsible for elimination of the virus. In the pre...

INTRODUCTION Few studies have focused on hepatitis B virus (HBV) infection among childbearing-age women. This study explored hepatitis B surface antigen (HBsAg) seroprevalence and hepatitis B e antigen (HBeAg) seroprevalence and their associated factors among childbearing-age women. METHODOLOGY A cross-sectional, population-based study was conducted between June 2013 and October 2013 in Miany...

It is common to observe the clustering of chronic hepatitis B surface antigen (HBsAg) carriers in families. Intra-familial transmission of hepatitis B virus (HBV) could be the reason for the familial clustering of HBsAg carriers. Additionally, genetic and gender factors have been reported to be involved. We conducted a three-stage genome-wide association study to identify genetic factors associ...

Hemophilia is the most common congenital coagulative disorder which exposes the patients to many problems because of lack of coagulative factors, higher risk of viral infections and other complications. This study was designed to detect the prevalence of hepatitis B and C infection in hemophiliac patients referring to Kerman Samenalhojaj Center. For this purpose, 97 hemophiliac patients were st...

Background: Approximately 600,000 deaths occur every year as a result of the acute and chronic consequences of hepatitis B virus infection. Ten different hepatitis B virus genotypes have been identified with distinct geographical distributions. Different clinical outcomes, including the rate of mutations, development of hepatocellular carcinoma, chronicity, response to treatment, transplantatio...

conclusions the palestinian and israeli official policies to give a booster dose for risk groups like medical students at anti-hbs level below 10 miu/ml should continue to ensure absolute protection. the currently-used vaccine and its time program cleared virus from students believed to have been exposed to the virus during their lifetime. background hepatitis b infection is a global public hea...