A 47-year-old woman presented with seizures secondary to euvolaemic hyponatraemia. A collateral history revealed recent increased oral fluid intake and increased use of herbal remedies including valerian root over the New Year period. There was no history of psychiatric disease to support psychogenic polydipsia. She responded to careful sodium replacement in the intensive care unit and was disc...

denominator of TEN development. A single or multiplier effect by idiosyncratic, dose-related or drug-interactive reactions of phytochemicals or contaminants might be involved in the development of TEN in these patients. The objective evaluation by the Naranjo adverse drug reaction (ADR) probability scale calculated a possible ADR by the herbal remedy in cases 1 and 3 and a probable cause in cas...

Snake bite is a major health hazard that leads to high mortality and great suffering in victims. The remedies are of great interest since they may have recognizable therapeutic or toxic effects and are steeped in cultural beliefs that invariably conflict with formal health care practices. The study of the interaction between plants and people is invaluable in discovering new herbal medicines an...

background: the increase in the use of herbal products is noticed all over the world. the safety of herbal drugs becomes particularly important in pregnant women and children. despite the fact that available data are insufficient to justify herbal use during pregnancy, exposure to herbal products is frequent in these subjects. some of the more complex reasons for preference of herbal medicine a...

AIMS There is an increase of over-the-counter (OTC) herbal products for use in diabetes mellitus. The aim of this study is to evaluate the safety information provided with OTC herbal remedies intended for diabetic patients in Sri Lanka and to assess the completeness of the information provided. METHODS Inclusion criteria consisted of OTC herbal remedies meant for use in diabetes. They were bo...

The use of alternative medicine is prevalent worldwide. However, its effect on intraoperative anesthetic care is underreported. We report the anesthetic management of a patient who underwent an extensive head and neck cancer surgery and presented with a severe intraoperative metabolic alkalosis from the long term ingestion of baking soda and other herbal remedies.

INTRODUCTION Autism is a complex neurodevelopmental disorder in which the interactions of genetic, epigenetic and environmental influences are thought to play a causal role. In humans, throughout embryonic and fetal life, brain development is exquisitely susceptible to injury caused by exposure to toxic chemicals present in the environment. Although the use of herbal supplements during pregnanc...

Premenstrual syndromes (PMS) are a group of menstrually related, chronic and cyclical disorders characterized by emotional, behavioral, and physical symptoms in the second half (luteal phase) of the menstrual cycle. Several line of evidence point to a significant role of the serotonergic system in the course of the luteal phase in women with PMS/ Premenstrual Dysphoric Disorder. It has been rep...

OBJECTIVE To report 2 cases of adverse reactions to St John's wort, a popular herbal treatment for depression. METHOD We present 2 case histories and review the existing literature regarding St John's wort. RESULTS St John's wort may cause serotonin syndrome in sensitive patients. In addition, St John's wort may be associated with hair loss. CONCLUSIONS For clinical reasons, it is importa...

Ethnopharmacology investigations classically involved traditional healers, botanists, anthropologists, chemists and pharmacologists. The role of some groups of researchers but not of physician has been highlighted and well defined in ethnopharmacological investigations. Historical data shows that discovery of several important modern drugs of herbal origin owe to the medical knowledge and clini...