Ocular infections with herpes simplex virus 1 can lead to corneal scarring and blindness, with herpes keratitis being the major infectious cause of blindness. There is currently no clinically approved vaccine and nearly all developmental vaccines are targeted against HSV-2 and genital herpes. We tested the ability of an HSV-2 replication-defective virus, a genital herpes vaccine candidate, to p...

Results: For labial herpes, the mean duration of attacks and pain, occurrence of crusting, and mean healing time with honey treatment were 35%, 39%, 28% and 43% better, respectively, than with acyclovir treatment. For genital herpes, the mean duration of attacks and pain, occurrence of crusting, and mean healing time with honey treatment were 53%, 50%, 49% and 59% better, respectively, than wit...

Antimony compounds are the cornerstone treatments for tegumentary leishmaniasis. The reactivation of herpes virus is a side effect described in few reports. We conducted an observational study to describe the incidence of herpes zoster reactivation during treatment with antimony compounds. The global incidence of herpes zoster is approximately 2.5 cases per 1,000 persons per month (or 30 cases ...

The Varicella Zoster virus persists in sensory nerve ganglion cells after chicken pox and gets reactivated to cause herpes zoster after variable periods of time as a result of waning of specific cellular immunity. Susceptible contacts of herpes zoster can develop chicken pox and very rarely herpes zoster. We report an interesting case of a father and his son who developed herpes zoster simultan...

background: herpes simplex viruses (hsv) are human pathogens that establish lytic and latent infections. reactivation from latency occurs intermittently, which represents a life-long source for recurrent infection. the role of immune factors in the control of recurrent symptomatic hsv lesions is complex and the exact role of cytokines remains unclear. objective: to assess the levels of tumor ne...

OBJECTIVE The purpose of this study was to determine whether the proportion of cesarean deliveries in pregnant women with a history of genital herpes and no active lesions at birth is higher than that in women with no history of genital herpes, and to determine whether this risk was modified by birth facilities' underlying prevalence of cesarean delivery. METHODS This was a retrospective surv...

objective: herpes simplex virus (hsvs) is a widespread human infectious agent, responsible for persistent and latent infections. herpes simplex virus infections are usually continually recurrent in the normal population and represent a significant cause of complications in immunocompromised patients. materials and methods: in this study hsvs were propagated in bk cells and more than 502 sample...

background: colorectal cancer is one of the most common malignancies worldwide with more than one million new cases diagnosed each year . the aim of this study is to investigate the prevalence of herpes simplex virus and epstein-barr virus in patients with colorectal carcinomas and polyps in comparison with healthy subjects by using the polymerase chain reaction technique. methods: in this anal...

A 25-year-old woman (gravida 2, abortion 1) was admitted to Ghaem Hospital affiliated to Mashhad University of Medical Sciences at 24th week of gestation. Her chief complaint was bloody show. She had a history of incompetent cervix, with premature labor at 22nd week of gestation. She was hospitalized with 4 cm dilatation and 50% effacement of cervix at 24th week of gestation. Following bed rest...

Herpes zoster occurs with increased frequency in patients with systemic lupus erythematosus (SLE). The aim of this study was to identify and evaluate clinical and laboratory risk factors associated with development of herpes zoster in patients with SLE. A retrospective case-control study was performed in a population of patients with SLE. Patients were identified as cases if their first episode...