OBJECTIVE To compare the relative proportions of varicella zoster virus (VZV) and herpes simplex viruses in specimens obtained from the genital lesions of adults presenting with presumed genital herpes infection. METHODS Swabs of genital lesions from 6210 patients attending general practices, infectious diseases clinics within hospitals, or sexual health centres for treatment of their genital...

The Herpes simplex viruses are responsible for a broad-spectrum of diseases affecting all age groups across the developed and developing world. The viruses are members of the herpesvirus family, which also includes the human pathogens Varicella-Zoster virus, Epstein-Barr virus, Cytomegalovirus, Human herpes virus -6 and -8. Herpes simplex virus type -1 (HSV-1) and -2 (HSV-2) are serotypically d...

OBJECTIVE To investigate the prevalence of herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) in the semen of men with fertility problems. DESIGN A descriptive clinical study. SETTINGS Outpatient infertility clinic of a private hospital. PATIENT(S) One hundred thirteen men attending an infertility clinic in Athens. INTERVENTION(S) Semen samples were collecte...

Background: Recent studies have suggested the role of herpes viruses in the etiopathogenesis of periodontal disease. Very few studies have explored the role of herpes virus in periodontal disease. The occurrence of herpes viruses may also vary depending on the race of the population studied. Herpes Simplex Virus (HSV 1&2) is frequently detected in gingival crevicular fluid of periodontal pocket...

PURPOSE Although a variety of malignant tumors are susceptible to therapy with oncolytic herpes simplex viruses, the determinants of tumor sensitivity to these viruses are poorly understood. Nectin-1 is a cell surface adhesion molecule that is a component of intercellular adherens junctions and also functions as a herpes viral receptor. Because highly invasive cells may have decreased intercell...

this study was conducted to evaluate the effects of administering oral acyclovir in conjunction with topical acyclovir and steroids in the treatment of necrotizing herpetic keratouveitis. all patients with necrotizing herpetic keratouveits who have been consulted during 1996-1997 at the farbi eye hospital were studied . the patients were randomly assigned to two groups. in the first group, topi...