نتایج جستجو برای: heterozygotes

تعداد نتایج: 4125  

Journal: :Blood 1992
D Rund D Filon N Strauss E A Rachmilewitz A Oppenheim

The relationship between the degree of microcytosis and the type of mutation carried by beta-thalassemia heterozygotes was investigated. In 113 individuals, 18 different mutations were identified, correlated with mean corpuscular volume (MCV) values, and analyzed statistically. Overall, there was a wide range of MCV (56.3-87.3 fL). In almost all cases, carriers of beta(0) mutations had an MCV b...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1966
J W Drake

Single-factor genetic crosses in bacteriophage T4 produce two distinct types of heterozygous progeny.' One kind probably corresponds to a terminal redundancy of the chromosome. The other kind, variously termed a heteroduplex heterozygote, an internal heterozygote, or a recombinational heterozygote, arises as an intermediate in recombination (Fig. 1). Internal heterozygotes are preferentially ac...

2017
Francesco Miragoli Sara Federici Susanna Ferrari Andrea Minuti Annalisa Rebecchi Eugenia Bruzzese Vittoria Buccigrossi Alfredo Guarino Maria Luisa Callegari

Cystic fibrosis is often associated with intestinal inflammation due to several factors, including altered gut microbiota composition. In this study, we analyzed the fecal microbiota among patients with cystic fibrosis of 10-22 years of age, and compared the findings with age-matched healthy subjects. The participating patients included 14 homozygotes and 14 heterozygotes with the delF508 mutat...

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