Over the last two decades there have been a growing number of designs for positron emission tomography (PET) cameras optimized to image the breast. These devices, commonly known as positron emission mammography (PEM) cameras allow much more spatial resolution by putting the photon detectors directly on the breast. PEM cameras have a compact geometry with a restricted field of view (FOV) thus ex...

ultrasound is one of the preferred modalities for evaluation of the parathyroid glands. this study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. from march 2008 to march 2009, ninety-one hemodialysis patients were examined by high resolution ultrasound (14 mhz) of the parathyroid glands in compari...

myelodysplastic syndromes (mdss) are a clonal bone marrow (bm) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (aml). methylation silencing of hrk has been found in several human malignancies. in this study, we explored the association of hrk methylation status with its expression, clinical parameters and mds subtypes in mds pa...

in the research, six degrees of freedom hexapod parallel machine tool is studied and investigated. jacobian matrix is developed by cinematic relations differentiation and using weighted coefficient method, dimensional analysis operation is carried out on jacobian matrix. geometric parameters of cartesian robot workspace are optimized, considering a minimum allowable rotation about three axes, a...

University of Texas MD Anderson Cancer Center, USA It is critically needed yet challenging to develop compact PET detectors with high sensitivity and uniform, high imaging resolution for improving the performance of simultaneous PET/MR imaging, particularly for an integrated/inserted small-bore system. Using the latest “edge-less” SiPM arrays for DOI measurement using the design of dual-ended-s...

We evaluate the MR compatibility of the Hyperion-II(D) positron emission tomography (PET) insert, which allows simultaneous operation in a clinical magnetic resonance imaging (MRI) scanner. In contrast to previous investigations, this work aims at the evaluation of a clinical crystal configuration. An imaging-capable demonstrator with an axial field-of-view of 32 mm and a crystal-to-crystal spa...

A small animal positron emission tomography (PET) instrument using a high-resolution solid-state detector insert in a conventional PET system was investigated for its potential to achieve sub-millimeter spatial resolution for mouse imaging. Monte Carlo simulations were used to estimate the effect of detector configurations (thickness, length and radius) on sensitivity. From this initial study, ...

UNLABELLED Detectors with depth-encoding allow a PET scanner to simultaneously achieve high sensitivity and high spatial resolution. METHODS A prototype PET scanner, consisting of depth-encoding detectors constructed by dual-ended readout of lutetium oxyorthosilicate (LSO) arrays with 2 position-sensitive avalanche photodiodes (PSAPDs), was developed. The scanner comprised 2 detector plates, ...

Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, NY, NY, USA Simultaneous MR/PET scanners allow for the exploration and development of novel PVE correction techniques without the challenges of coregistration of MR and PET. The development of a wavelet-based PVE correction method, to improve PET quantification, has proven successful in brain PET. We report ...

We are developing a high-resolution, high-efficiency positron emission tomography (PET) detector module with depth of interaction (DOI) capability based on a lutetium oxyorthosilicate (LSO) scintillator array coupled at both ends to position-sensitive avalanche photodiodes (PSAPDs). In this paper we present the DOI resolution, energy resolution and timing resolution results for complete detecto...