نتایج جستجو برای: high risk breast cancer
تعداد نتایج: 3546580 فیلتر نتایج به سال:
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
Introduction: Breast cancer is the most common cancer in women. Patients are treated with chemotherapy initially, and if not chemically treated, the risk of recurrence of the disease increases yearly. Therefore, methods for identifying patients for whom chemotherapy would be most beneficial are very important. The Oncotype DX test is a prognostic assay that predicts the likelihood of breast can...
Breast cancer is the most commonly diagnosed invasive cancer among women. Many factors, both genetic and non-genetic, determine a woman's risk of developing breast cancer and several breast cancer risk prediction models have been proposed. It is vitally important to risk stratify patients as there are now effective preventive strategies available. All women need to be counseled regarding health...
obesity is an important public health problem and major risk factor for postmenopausal breast cancer. adipose tissue is the major component involved in the control of the metabolism through energy homeostasis, adipocyte differentiation, insulin sensitivity and the activation of anti-inflammatory metabolic and immune pathways. leptin and adiponectin pathways are involved in proliferation process...
Random periareolar fine needle aspiration (RPFNA) and ductal lavage (DL) are research techniques developed to (1) assess short-term breast cancer risk in asymptomatic women who are at increased risk for breast cancer and (2) track cytological response to risk reduction strategies. RPFNA and DL provide minimally invasive methods to repeatedly sample epithelial cells and research tools to investi...
background: vitamin d has a wide range of physiological functions in skeletal and nonskeletal tissues which may play a role in many diseases. the aim of this study was to evaluate the recent evidence regarding the effects of vitamin d on several health outcomes in women including breast cancer, ovarian and endometrial cancers, hypertension, and osteoporosis. materials and methods: we searched ...
Background & Aims: Considering the increasing prevalence of breast cancer, today, the main problem in the field of women's health is the control and prevention of breast cancer. One of the main areas in preventing this disease is controlling the risk factors associated with lifestyle. Wearing of brassiere is also a lifestyle-related habit that has sparked many debates today as a risk factor for...
Sporadic breast cancer develops through the accumulation of molecular abnormalities in normal breast tissue, resulting from exposure to estrogens and other carcinogens beginning at adolescence and continuing throughout life. These molecular changes may take a variety of forms, including numerical and structural chromosomal abnormalities, epigenetic changes, and gene expression alterations. To c...
cancer is uncontrolled and unrestricted growth of malignant cells in the body. it is a multifactorial disease which either heredity or environmental factors (such as nutrition, physical inactivity, alcohol, obesity, exposure to sun, environmental pollutants, infections) contribute to the incidence of cancer. in recent years, several lines of research have focused on obesity as a potent risk fac...
BACKGROUND Endogenous sex hormone levels have been associated with increased breast cancer risk in postmenopausal women in several prospective studies. However, it remains unclear to what extent serum hormone-breast cancer associations differ with receptor status. METHODS Associations between serum sex hormone levels and breast cancer risk were assessed in a nested case-control study on postm...
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