نتایج جستجو برای: histamine h1 receptor

تعداد نتایج: 612417  

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2011

2005
Jeong-Hee Choi Seung-Hyun Kim Chang-Hee Suh Dong-Ho Nahm Hae-Sim Park

The pathogenic mechanism of ASA-induced urticaria/angioedema (AIU) is still poorly understood, but it has been known that histamine releasing by cutaneous mast cell activation is considered to be an important role. Considering the importance of histamine in AIU, we speculated that a genetic abnormality of histamine-related genes such as a high-affinity IgE receptor, a metabolic enzyme of histam...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009
Michio Senda Nobuo Kubo Kazuhiko Adachi Yasuhiko Ikari Keiichi Matsumoto Keiji Shimizu Hideyuki Tominaga

UNLABELLED Some antihistamine drugs that are used for rhinitis and pollinosis have a sedative effect as they enter the brain and block the H(1) receptor, potentially causing serious accidents. Receptor occupancy has been measured with PET under single-dose administration in humans to classify antihistamines as more sedating or as less sedating (or nonsedating). In this study, the effect of repe...

Journal: :International Journal of Modeling and Optimization 2015

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