The identification of protein targets for organic small molecules, and characterization of these chemical compounds, is of fundamental importance for drug discovery research. Here we describe the application of LeadCode TM technology, developed by GPC Biotech for the proteome-wide identification of protein targets and array-based profiling of kinase inhibitors. LeadCode TM utilizes yeast-three-...

Beginning January 1, 2010, the Centers for Medicare & Medicaid Services (CMS) increased the focus on depression screening and care planning for older adults receiving home health care services. With this revision, Medicare-certified home care agencies are required to complete two new depression related items included in the Outcome and Assessment Information Set (OASIS-C). These home health car...

Microalgae possess great potential as a source of sustainable energy, but the intrinsic inefficiency of photosynthesis is a major challenge to realize this potential. Photosynthetic organisms evolved phototaxis to find optimal light condition for photosynthesis. Here we report a microfluidic screening using competitive phototaxis of the model alga, Chlamydomonas reinhardtii, for rapid isolation...

BACKGROUND Breast cancer is the most common cancer afflicting women in Jordan. This study aimed to assess the effects of an educational intervention through home visits, including offering free mammography screening vouchers, on changing women's breast health knowledge and screening practices for early detection of breast cancer in a less privileged area in Jordan. METHODS Two thousand four h...

This study examined the relationship between the neighborhood food environment and the food purchasing behaviors among adolescents. Grade 7 and 8 students (n = 810) at 21 elementary schools in London, Ontario, Canada completed a questionnaire assessing their food purchasing behaviors. Parents of participants also completed a brief questionnaire providing residential address and demographic info...

background: heat stress is a common and usual problem in industries. several indices, including wet bulb globe temperature (wbgt), are used to evaluate heat stress. however, wbgt index has limitations such as high cost and response time. it is not thus suitable as a screening tool. heat strain scoring index (hssi) is also an observational-judgmental technique that has been developed for primary...

P.Augusta Sophy Butterfly Elements , R.Srinivasan, J.Raja, S.Anand Ganesh # School of Electronics, VIT University, Chennai, India * Department of Electronics & Communication Engineering, SSN College of Engineering, Chennai, India $ Department of Electronics & Communication Engineering, Sai Ram Engineering College, Chennai, India. [email protected] [email protected] rajajanakiraman@...