To assess the performance criteria of the reinforced-concrete, five-storey residential buildings common in Iran, an experimental study in the structural laboratory of the University of Tehran has been conducted. The test program includes cyclic and monotonic load tests of six beams that represent three-to-five storey buildings with rigid frame structures. Using definitions given in FEMA-356 a...

background: the pabon lasso model was  applied to assess the performance of six state-run hospitals in the province of kohgilooyeh & boyer-ahmad, to produce information that used by policy makers in their attempt to make the health care sys­tem more productive. methods: this cross-sectional study involved all the six public hospitals in the province, with 607 registered beds. data collec­tion a...

Occupancy information is commonly regarded as an important ingredient for energy efficient building climate control. In a recent study of the authors, the energy savings potential of using long-term occupancy information (in the range of days) in the control of office buildings was investigated, assuming a geometric distribution of occupancy and vacancy intervals. In this work, the findings of ...

The packaging of DNA into nucleosomes influences the accessibility of underlying regulatory information. Nucleosome occupancy and positioning are best characterized in the budding yeast Saccharomyces cerevisiae, albeit in asynchronous cell populations or on individual promoters such as PHO5 and GAL1-10. Using FAIRE (formaldehyde-assisted isolation of regulatory elements) and whole-genome microa...

Dopamine D(2) receptor occupancy of antipsychotic drugs is calculated relative to the subject's D(2) receptor binding potential (BP) in the drug-free state (baseline BP). Because baseline BP is seldom known in patients with schizophrenia, population means from unrelated control samples are often used to estimate it. However, this is likely to introduce bias and error into the occupancy measure....

UNLABELLED The aim of this study was to assess human striatal dopamine receptor 2 (D(2)) and cortical 5-hydroxytryptamine receptor 2A (5-HT(2A)) occupancy of SB-773812 to demonstrate brain penetration and binding to the target receptors and assess the pharmacokinetics-receptor occupancy relationship over time to aid dose selection and dosage regimen, in preparation for the phase II trials. ME...