RNA replication of Cymbidium ringspot virus (CymRSV) normally occurs in plant and yeast cells in association with membranes derived from peroxisomes. However, in yeast strains devoid of these organelles CymRSV RNA replication takes place on the perinuclear membrane and cytoplasmic endoplasmic reticulum (ER) strands. The association of the CymRSV RNA replication complex to ER is mediated by the ...

Developing murine growth plates comprise at least three morphologically distinct groups of chondrocytes (see Fig. 3C): round periarticular chondrocytes, flat columnar chondrocytes and hypertrophic chondrocytes. Periarticular chondrocytes proliferate and differentiate into columnar chondrocytes that proliferate further and form orderly columns. Unlike the round periarticular chondrocytes, the fl...

In the preface to this book the author states, " I have endeavoured to present a practical guide to the differential diagnosis and treatment of indigestion." This is a worthy aim, for it is probable that the general practitioner finds more difficulty in diagnosing the cause and directing the treatment of indigestion than he does in any other common complaint. In the popular textbooks the chapte...

In motor imagery-based Brain Computer Interfaces (BCI), discriminative patterns can be extracted from the electroencephalogram (EEG) using the Common Spatial Pattern (CSP) algorithm. However, the performance of this spatial filter depends on the operational frequency band of the EEG. Thus, setting a broad frequency range, or manually selecting a subject-specific frequency range, are commonly us...

CD47 inhibits phagocytosis and its overexpression is correlated with poor prognosis in patients with several types of cancer. It has also been reported that CD47 expression in multiple sclerosis is regulated by microRNAs. However, the regulatory mechanism of CD47 in cancer tissues has not been yet clarified. Re-analysis of a public microarray database revealed that miR-133a is downregulated in ...

Acute myeloid leukemia (AML) is a hematological malignancy with a low survival rate. Curcumin, which is a multi-targeted anticancer agent, has been shown to exert anti‐oxidant, anti‐inflammatory, anti‐mutagenic and anti-carcinogenic activities. Naringenin is extracted from citrus fruits and exerts anti-mutagenic and anti-carcinogenic activities in various types of cancer cells. However, the eff...

Interleukin-2 (IL-2) activates several different families of tyrosine kinases, but precisely how these kinases interact is not completely understood. We therefore investigated the functional relationships among Jak3, Lck, and Syk in IL-2 signaling. We first observed that in the absence of Jak3, both Lck and Syk had the capacity to phosphorylate Stat3 and Stat5a. However, neither supported IL-2-...

5(S),6(R)-7-trihydroxymethyl heptanoate (BML-111) is an lipoxin A4 receptor agonist, which modulates the immune response and attenuates hemorrhagic shock-induced acute lung injury. However, the role of BML-111 in sepsis and in the intestinal mucosal barrier are not well understood. Therefore, the present study was designed to investigate the effect of BML-111 on the intestinal mucosal barrier i...

This paper proposes a fast algorithm for Walsh Hadamard Transform on sliding windows which can be used to implement pattern matching most efficiently. The computational requirement of the proposed algorithm is about 1.5 additions per projection vector per sample which is the lowest among existing fast algorithms for Walsh Hadamard Transform on sliding windows.