Objective: The aim of this study was to compare the efficacy of HPV 16/18 genotyping test, high risk HPV DNA testing, alone and in conjunction with the liquid-based cytology method in screening for cervical cancer precursors. Methods: A Markov model was used to describe the course of the cases of CIN2+ that had been detected over a 35 year period. Screening programs started at age 30 and were p...

BACKGROUND The cobas HPV Test ("cobas"; Roche Molecular Systems) detects HPV16 and HPV18 individually, and a pool of 12 other high-risk (HR) HPV types. The test is approved for (i) atypical squamous cells of undetermined significance (ASC-US) triage to determine need for colposcopy, (ii) combined screening with cytology ("cotesting"), and (iii) primary HPV screening. METHODS To assess the pos...

Background: A plethora of data supports HPV-based screening to be the preferred strategy for cervical cancer prevention. The shift a more sensitive first-line test brings need effective triage up discussion. Currently, most algorithms apply cytology as HPV-DNA positive women. This study compared performance 7-type HPV-mRNA cytology. Methods: From 1 January 2019 until 31 December 2021, samples f...

inverted follicular keratosis (ifk) a benign tumor of skin appendages which is mostly presented as a solitary nodule with keratotic or scaling surface on the face of a middle aged or old patients but it can develop in other parts of the body. different studies have lead to development of different theories about the role of human papillomavirus (hpv) in this kind of skin tumor. the purpose of t...

High prevalence of human papillomavirus (HPV) infection, its causative role in the development of cervical cancer and heterogeneity of HPV types indicate that HPV infection is not only medicobiological problem but also has a social significance. Currently, an HPV DNA test is recommended by international organizations (ASCCP, EUROGIN, IARC WHO) for applying in population screening. For virus-pos...

conclusions our study shows that prevalence of hpv infection in cervical biopsy samples collected from suspected patients in khouzestan province is slightly higher than other provinces of iran. since hpv cervical infection, is an indicator for the host cervical cancer progression, parallel with pap smear test, pcr detection of hpv dna in biopsy of suspected cases is recommended. results out of ...

BACKGROUND In French Guiana, cervical cancer is the second most frequent cancer in females. The objective of the present study was to describe the prevalence of HPV infections in women with normal cervical cytology living in the remote villages of French Guiana. METHODS Before the study, the study team communicated in the remote villages on the importance of screening. All women from the targ...

OBJECTIVES Testing for human papillomavirus (HPV) infection has recently been introduced into cervical screening programmes. We investigated (1) barriers to accessing and absorbing information and (2) factors that influence information needs among women undergoing HPV tests. METHODS In-depth interviews were conducted with 27 women who had HPV tests performed in a colposcopy clinic as part of ...

Hybrid Capture 2 (hc2), a clinical test for carcinogenic human papillomavirus (HPV) DNA, has proven to be a sensitive but only modestly specific predictor of cervical precancer and cancer risk. Some of its nonspecificity for clinical end points can be ascribed to cross-reactivity with noncarcinogenic HPV genotypes. However, the reference genotyping tests that have been used for these comparison...