Epigallocatechin gallate (EGCG) (Figure 1a) is the major catechin component of green tea (Camellia sinensis). It has been shown to have antiviral properties against DNA viruses such as herpes simplex virus (HSV; Herpesviridae) [1], adenovirus (Adenoviridae) [2], human papilloma virus (HPV; Papovaviridae) [3], and hepatitis B virus (HBV; Hepadnaviridae) [4], and RNA viruses such as influenza vir...

During 1984 the British Co-operative Clinical Group undertook a survey of genitourinary medicine clinics in the United Kingdom to assess the availability of laboratory diagnostic facilities for Chlamydia trachomatis and herpes simplex virus. Of the 115 clinics assessed, 68% (78) had adequate facilities for culture for C trachomatis and 87% (100) for herpes simplex virus.

We presented four cases diagnosed with Herpes simplex virus encephalitis of those treated in our clinic in 2006 one of whom died, one recovered without any sequels. Two cases were left with advanced motor mental sequel. In this paper, clinical and laboratory findings along with diagnosis and treatment of Herpes simplex virus encephalitis were discussed.

Herpes simplex virus type 2 (HSV-2) infections are frequent in HIV (human immunodeficiency virus) infected patients. In those cases, genital herpes may have an atypical clinical presentation. Hypertrophic and vegetating variants are unusual. The authors describe a case of hypertrophic perianal herpes in an HIV patient with unsatisfactory response to acyclovir and valacyclovir, successfully trea...

Purpose To report a case of hypertrophic herpes simplex virus (HSV) of the eyelid and cornea masquerading as IgG4-related disease. Observations A 37-year old African American female with a past medical history of human immunodeficiency virus (HIV) on highly active antiretroviral therapy (HAART) and a recent history of treated genital herpes, presented with an ulcerative lesion of the left upp...

Received: October 02, 2015; Accepted: October 20, 2015; Published: October 23, 2015 Abbreviations: PML: Progressive Multifocal Leukoencephalopathy; JCV: John Cunningham Virus; AIDS: Acquired Immune Deficiency Syndrome; CSF: Cerebrospinal Fluid; HIV: Human Immuno deficiency Virus; HSV: Herpes Simplex Virus; VZV: Varicella Zoster Virus; CMV: Cytomegalovirus; ADC: Apparent Diffusion Coefficient; S...

Cord serum samples treated with staphylococcus protein A and an immune affinity column to remove immunoglobulin G were used to establish a seronegative range for herpes simplex virus and cytomegalovirus. No seroconversions or increased heterologous antibody levels to herpes simplex virus or cytomegalovirus were found in live varicella vaccine recipients.

A late preterm neonate born by cesarean section with intact membranes presented at 9 days of life with shock and liver failure. Surface cultures were negative but whole blood polymerase chain reaction was positive for herpes simplex virus type 2, underscoring the value of this test in early diagnosis of perinatally acquired disseminated herpes simplex virus infection without skin lesions.

The herpes simplex virus 1 ICP27 is an essential, highly conserved protein involved in various steps of herpes simplex virus 1 gene regulation as well as in the shut-off of host gene expression during infection. It functions primarily at the post-transcriptional level in inhibiting precursor mRNA splicing and in promoting nuclear export of viral transcripts. These activities are discussed.