Purpose: To investigate the frequency, localization, and survival of second primary tumors (SPT) oropharyngeal squamous cell carcinoma (OPSCC) depending on human papillomavirus (HPV) status. Methods: We performed a retrospective chart analysis 107 OPSCC patients treated at Zurich University Hospital from 2001 to 2010. Rate localization SPT after an index were stratified according smoking HPV in...

Cancer is one of the most prevalent causes mortality worldwide. In cervix, it confirmed to be caused by different high-risk human papillomavirus (HPV) types. Although many studies have already been conducted worldwide on epidemiology HPV infection and their oncogenic properties, limited data are available prevalence, incidence its impacts in Egypt.

Senescence is blocked in human cervical keratinocytes infected with high risk human papillomavirus (e.g. HPV type16). Viral oncoproteins HPV E6 and HPV E7 access the cell cycle via cellular p53 and retinoblastoma proteins respectively. Previously we have shown that HPV E7, not HPV E6, is also responsible for cervical cancer cell survival (SiHa cells; HPV type16). We now present evidence that SI...

Background In contrast to adults, only limited data are available on the human papillomavirus (HPV)-type spectrum in anogenital warts (AGW) of children. Objective This study aimed evaluate HPV-type AGW prepubertal Materials & methods a retrospective German multicentre study, HPV genotyping was performed biopsies 55 1- 12-year-old children using group-specific PCRs followed by hybridization with...

results hpv-16 e6 and e7 proteins reduced e-cadherin expression 3.7 and 2.2 times when compared with control cells (p = 0.0221 and p = 0.0461, respectively). this reduction was greater in hpv-16 e6-expressing cells than in hpv-16 e7-expressing cells. although hpv-16 e6 and e7 increased dna methyltransferase 1 expression 2.6 and 3.4 times, respectively (p = 0.0133 and p = 0.0113) when compared w...

Human Papillomavirus (HPV) is the main cause of cervical cancer. In last decade, mortality rate due to cancer has increased alarmingly in world, especially some countries, such as Brazil. eyes science, it absurd admit a fact, since this only that vaccine and highly effective, addition being an easily diagnosed treatable disease its early stages. A failure communication related HPV forms prevent...

Infection with the human papillomavirus (HPV) has been identified as a major risk factor for oropharyngeal cancer (OPC). HPV-related OPCs have shown to be more radiosensitive and reduced related death. Hence, histological determination of HPV status patients depicts an essential diagnostic factor. We investigated ability deep learning models imaging based detection. To overcome problem small me...

Background: Breast cancer is the malignancy in humans and other mammals. Several risk factors are involved in their appearance such as higher hormone levels and obesity. Identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. Viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...

The worldwide incidence of skin cancer has dramatically increased. The genetic, hormonal and environmental factors are involved in the development of skin cancer. Recently, human papillomaviruses are considered to play an important part in skin cancer etiopathogeny. Human papillomaviruses produce epithelial tumours of skin and mucous membranes. The number of patients identified with human papil...