Felodipine is a long-acting 1, 4-dihydropyridine calcium channel blocker, used to control hypertension by selective action on peripheral resistance. The conventional felodipine tablet gives a rather high peak and comparatively low trough levels, due to rapid absorption and distribution. More sustained plasma concentrations might thus produce a more even effect on blood pressure. The main aim of...

Formulations for sustained medication release are very useful in the treatment of chronic disorders. The oral route has selected matrix tablets as most likely type prolonged drug release. In order to generate therapeutic activity a protracted duration, maintain stable plasma concentration and sustain rate throughout time. preparations with short half-life high dosage frequency, extended-release...

Minimizing loss of injected hydraulic fracturing fluids into shale along fracture-matrix boundaries is desired because imbibed water restricts gas production and wastes valuable resources. This problem has motivated the addition surfactants water-based in order to reduce capillary driving force for imbibition. Here, we show that reduction interfacial tension wettability alteration negligible ab...

Hydrophobic grade fumed silicas are generally used in tabletting as lubricants. They are also found to retard the release of pharmaceutical actives. This is because of their hydrophobic nature, which gives good cohesive and adhesive properties. considering this point it was thought that they could be used as dry coating agents for solid dosages forms. The model drug selected for this work was p...

the surface parameter of nanoparticles such as hydrophobicity and a hydrophilicity on protein structure and function is very important. in this study, conformational changes of glucose oxidase (gox) in the mercaptopurine: gnps and 11-mercaptoundecanoic acid: gnps as a hydrophobic and a hydrophilic gnps surface was investigated by various spectroscopic techniques, including: uv-vis absorption, f...

titanium dioxide (tio2)nanoparticles have been frequently employed in the environmental treatment and purification purposes as a cheap and highly efficient photocatalyst. a photocatalyst can facilitate the breakdown and removal of a variety of environmental pollutants at room temperature. tio2 photocatalyst is the best candidatebecause of its strong oxidized ability, non-toxicity and longtherma...

Cyclodextrins (CDs) have been used by the pharmaceutical and food industries since 1970s. Their cavities allow accommodation of several hydrophobic molecules, leading to formation inclusion complexes (ICs) increasing guest molecules’ stability, allowing their controlled release, enhancing water solubility biodisponibility. Due these, CDs ICs proposed be as potential allies in packaging, especia...