Objective To examine the cost and cost effectiveness of quarterly CD4 cell count and viral load monitoring among patients taking antiretroviral therapy (ART). Design Cost effectiveness study. Setting A randomised trial in a home based ART programme in Tororo, Uganda. Participants People with HIV who were members of the AIDS Support Organisation and had CD4 cell counts <250 ×10 cells/L or World ...

The paper ‘Cognitive load predicts point-of-care ultrasound simulator performance’ by Aldekhyl, Cavalcanti, and Naismith, in this issue of Perspectives on Medical Education [1], is an important paper that adds to work on cognitive load theory and medical education [2–4]. The implications of the findings of this paper extend substantially beyond the confines of medical practice that is the focus...

OBJECTIVE We studied the association of digestible carbohydrates, fiber intake, glycemic index, and glycemic load with insulin sensitivity (S(I)), fasting insulin, acute insulin response (AIR), disposition index, BMI, and waist circumference. RESEARCH DESIGN AND METHODS Data on 979 adults with normal (67%) and impaired (33%) glucose tolerance from the Insulin Resistance Atherosclerosis Study ...

OBJECTIVE We systematically reviewed the performance of 2010 WHO immunologic and clinical criteria for predicting virologic failure in HIV-infected patients on antiretroviral therapy (ART). DESIGN Systematic review. METHODS We used Cochrane Collaboration methods. We calculated unweighted sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of immuno...

JIANZHONG AN, SRINIVASAN G. VARADARAJAN, AMADOU CAMARA, QUN CHEN, ENIS NOVALIJA, GARRETT J. GROSS, AND DAVID F. STOWE Anesthesiology Research Laboratories, Departments of Anesthesiology, Physiology, and Pharmacology and Toxicology, and Cardiovascular Research Center, The Medical College of Wisconsin, Milwaukee 53226; and Research Service, Veterans Affairs Medical Center, Milwaukee, Wisconsin 53295