BACKGROUND The aim of this study was to investigate whether any esophageal motor dysfunction exists in patients with iron deficiency anemia (IDA). METHODS The study included 39 patients (34 women, mean age: 44.17 ± 14.21 years) who met WHO diagnostic criteria for IDA. An additional 30 functional dyspepsia patients were also included as a control group. Esophageal motility testing was performe...

Two new eudesmane sesquiterpenes, 2alpha-hydroxy pterodontic acid (1) and pterodolide [3alpha-(2-methyl-2,3-epoxy)-butyric-4alpha-acetoxy-8beta-ethoxy eudesma-7(11)-en-8alpha,12-olide (2), along with five known compounds (3-7) were isolated from the aerial parts of Laggera pterodonta. Their structures were elucidated on the basis of spectroscopic methods. The immunosuppressive activity of the i...

hepatobiliary scintigraphy is a sensitive method for intra & extera hepatic bile leak diagnosis. bile lead may be seen after hepatobiliary surgery, trauma, inflammatory disease or malignant neoplasms. although sonography and ct scanning are useful for diagnosis of peritoneal or perihepatic fluid, they cannot prove bile ascites. hepatobiliary scintigraphy with tc-99m-ida agents is a physiolo...

BACKGROUND The aim of this study was to investigate the urine levels of human kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), N-acetyl-β-D-glucosaminidase (NAG), and liver-type fatty acid-binding protein (L-FABP) in children with iron-deficiency anemia (IDA). MATERIAL AND METHODS Thirty-five children with IDA and 32 matched healthy controls were recruited....

BACKGROUND/AIMS Helicobacter pylori (H. pylori) infection appears to subvert the human iron regulatory mechanism and thus upregulates hepcidin, resulting in unexplained iron-deficiency anemia (IDA). We evaluated serum prohepcidin levels before and after eradication of H. pylori in IDA patients to assess whether it plays a role in IDA related to H. pylori infection. METHODS Subjects diagnosed ...

Direct lineage reprogramming through genetic-based strategies enables the conversion of differentiated somatic cells into functional neurons and distinct neuronal subtypes. Induced dopaminergic (iDA) neurons can be generated by direct conversion of skin fibroblasts; however, their in vivo phenotypic and functional properties remain incompletely understood, leaving their impact on Parkinson's di...

This longitudinal study investigated the rates of iron-deficiency (ID) and iron-deficiency anemia (IDA) among prenatally cocaine-exposed and nonexposed two- and four-year-old children and assessed their relationships to neurodevelopmental outcomes. The sample consisted of 143 two-year-old (70 exposed and 73 nonexposed) and 274 four-year-old (139 exposed and 135 nonexposed) low socioeconomic sta...

Epidemiology In the developed world, 2-5% of adult men and postmenopausal women have IDA. [4] Iron deficiency and IDA are common in young children. [5] Iron deficiency is the most common cause of anaemia in pregnancy worldwide; severe anaemia can have very serious consequences for mothers and babies. [6] Premenopausal women have a higher incidence of IDA because of heavy menstrual blood losses ...

Background: the Iron deficiency anemia (IDA) is a common cause of referral to medical departments. Chronic gastrointestinal (GI) blood loss is important cause of IDA and also an alarming sign of serious underlying disease. The information concerning ideal evaluation of the gastrointestinal tract in patients with the IDA is scant. We designed a prospective study to determine the frequency of GI ...