Liver cirrhosis is a chronic liver infection. It consist of deterioration cells along with fibrosis and infection generating nodules. Patients frequently have either global malnutrition or alterations in specific aspects nutritional status, such as micronutrient deficiencies, due to multiple mechanisms, including poor intake, absorption, increased losses. In addition, one the most significant p...

Granulomatous hepatitis may present with abdominal pain. Four patients are described who had longstanding severe abdominal pain associated with this condition.

Introduction: Neonatal jaundice is the most common cause of hospitalization.Animal study demonstrated a decrease in serum bililrubin level after zinc treatment in hyperbilirubinemic rats. The objective of this study was the investigation of serum zinc level in the neonates with idiopatic .   Materials and Methods: A case-control study was undertaken on 263 neonates in a neonatal intensive care ...

BACKGROUND Liver cirrhosis is one of the major causes of hospitalization and mortality in children. A wide spectrum of disorders including developmental abnormalities, infections, metabolic and genetic disorders can lead to liver cirrhosis in pediatric patients. Determination of its etiology is important for treatment, prevention of progressive liver damage, family counseling and prioritizing l...

chronic liver diseases in children is the result of many different diseases including: metabolic, genetic, infectious, toxic and idiopathic causes. this was a case series study on 133 infants and children with age range 6 month to 12 years old, who presented clinically with manifestation of chronic liver disease and were admitted to children hospital medical center from year 1999 to 2000. in th...

Between June 1994 and November 2001, 87 patients underwent living-related liver transplantation at our hospital. Forty-seven of the patients were men and 40 women, with a mean age ( standard deviation) at the time of transplantation of 13.0 18.7 years. The 87 recipients presented with the following indications: biliary atresia (n 53), hepatitis B-related liver cirrhosis (n 8), hepatitis B-relat...

CONTEXT Neonatal cholestasis (NC) lasting more than 2 weeks affects one in 2500 live births. Extrahepatic biliary atresia (EHBA) and idiopathic neonatal hepatitis account for about 70% of all cases of NC. Differentiating these two conditions is important as patient management is very different for both the conditions. AIMS To assess the usefulness of the seven-feature, 15-point histological s...

Retroperitoneal fibrosis (RPF) is a rare, progressive disease characterized by chronic non specific inflammation of the retroperitoneum. Although the pathogenesis of idiopathic retroperitoneal fibrosis (IRF) remains unclear, IRF has been reported in association with autoimmune disorders. However, few cases of IRF associated with rheumatoid arthritis (RA) have been reported. We experienced a rar...

Preterm labor (PTL) is a major cause of neonatal morbidity and mortality worldwide. Among the available tocolytics, indomethacin, a prostaglandin synthetase inhibitor, has been in use since the 1970s. Recent studies have suggested that prostaglandin synthetase inhibitors are superior to other tocolytics in delaying delivery for 48 hours and 7 days. However, increased neonatal complications incl...

PURPOSE We investigated the etiology of acute hepatitis in three children with systemic Juvenile Idiopathic Arthritis (sJIA) taking Interleukin-1 receptor antagonist (IL1RA). METHODS Laboratory and clinical data for three children with sJIA diagnosed at ages 13 months to 8 years who developed acute hepatitis during treatment with IL1RA were reviewed for evidence of sJIA flare, infection, macr...