Recurrent pregnancy loss (RPL) also referred to as recurrent miscarriage or recurrent spontaneous abortion has been a cause for bad obstetric history along with still births, intrauterine fetal deaths and intrauterine growth retardation (IUGR). According to the Practice Committee of the American Society for Reproductive Medicine, for epidemiological studies, three or more pregnancy losses are c...

Recurrent pregnancy loss (RPL) also referred to as recurrent miscarriage or recurrent spontaneous abortion has been a cause for bad obstetric history along with still births, intrauterine fetal deaths and intrauterine growth retardation (IUGR). According to the Practice Committee of the American Society for Reproductive Medicine, for epidemiological studies, three or more pregnancy losses are c...

Recurrent pregnancy loss (RPL) is a multifactorial condition. Approximately half of patients with RPL will have no explanation for their miscarriages. De novo chromosome abnormalities are common in sporadic and recurrent pregnancy loss. Testing for embryonic abnormalities can provide an explanation for the miscarriage in many cases and prognostic information. Regardless of the cause of RPL, pat...

BACKGROUND Recurrent pregnancy loss (RPL) is a common health problem. The polymorphisms G20210A of prothrombin gene (FII G 20210A), and G 1691A of factor V gene (Factor V Leiden, FVL) are the most extensively studied thrombophilic mutations in association to recurrent miscarriage. OBJECTIVES To determine the frequency of FII G20210A and FVL polymorphisms as well as protein C and protein S def...

Recent evidences associate thrombophilia with adverse pregnancy outcome. Numerous studies confirm Factor V Leiden (FVL) and Prothrombin G20210A (PT G20210A) mutations as important thrombophilia risk factors in Caucasians. However, these mutations are rare in Asians and thrombophilia investigations are therefore considered irrelevant in these patients. Hence, the status of thrombophilia-induced ...

Background/objective: Studies of the decidual leukocyte populations in women suffering from spontaneous early pregnancy loss may provide insight into immunpathological aspects and even cast light on the etiology of recurrent spontaneous abortion.Methods: In order to clarify the immunological role of endometrial leukocytes in repetitive abortion of unknown etiology, a comparative analysis of phe...

Background -Recurrent pregnancy loss defined as two or more miscarriage before 20 weeks of pregnancy affecting 1-5 % or women in reproductive age .There are many etiologies have been suggested, like Genetic, Immunologic, Thrombophila, Endocrine and Anatomic; but in 50% of cases, the exact etiology remains uncertain. Endometrium acts as biosensor of embryo quality and endometrium itself contribu...