The Autographa californica multinucleocapsid nuclear polyhedrosis virus (AcMNPV) ie-1 gene product (IE-1) is thought to play a central role in stimulating early viral transcription. IE-1 has been demonstrated to activate several early viral gene promoters and to negatively regulate the promoters of two other AcMNPV regulatory genes, ie-0 and ie-2. Our results indicate that IE-1 negatively regul...

The eukaryotic 60S-ribosomal stalk is composed of three P ribosomal proteins (P0, P1 and P2) which associate in a pentameric structure [2P1, 2P2, P0] in the ribosome. The Plasmodium falciparum protein P2 (PfP2) appears to play non-ribosomal roles. It gets exported to the infected erythrocyte (IE) surface at 30 hrs post merozoite invasion (PMI), concomitant with extensive oligomerization. Here w...

Interoceptive exposure (IE) is an effective procedure for reducing anxiety sensitivity (AS) and the symptoms of panic disorder. However, considerable variance exists in how IE is delivered among clinicians, and the extent to which IE is enhanced by the concurrent use of cognitive restructuring (CR) and diaphragmatic breathing (DB) is unclear. Participants (N = 58) with high AS were randomly ass...

OBJECTIVES To update the epidemiology of S. aureus bloodstream infection (SAB) in a high-income country and its link with infective endocarditis (IE). METHODS All consecutive adult patients with incident SAB (n = 2008) were prospectively enrolled between 2009 and 2011 in 8 university hospitals in France. RESULTS SAB was nosocomial in 54%, non-nosocomial healthcare related in 18% and communi...

Interoceptive exposure (IE) is an effective procedure for reducing anxiety sensitivity (AS) and the symptoms of panic disorder. However, considerable variance exists in how IE is delivered among clinicians, and the extent to which IE is enhanced by the concurrent use of cognitive reappraisal (CR) and diaphragmatic breathing (DB) is unclear. Participants (N 5 58) with high AS were randomly assig...

for a simple connected graph $g$ with $n$-vertices having laplacian eigenvalues‎ ‎$mu_1$‎, ‎$mu_2$‎, ‎$dots$‎, ‎$mu_{n-1}$‎, ‎$mu_n=0$‎, ‎and signless laplacian eigenvalues $q_1‎, ‎q_2,dots‎, ‎q_n$‎, ‎the laplacian-energy-like invariant($lel$) and the incidence energy ($ie$) of a graph $g$ are respectively defined as $lel(g)=sum_{i=1}^{n-1}sqrt{mu_i}$ and $ie(g)=sum_{i=1}^{n}sqrt{q_i}$‎. ‎in th...

Background Echocardiography plays a central role in diagnosing infective endocarditis (IE). Accordingly, the European Society of Cardiology (ESC) has proposed a diagnostic echocardiographic algorithm. However, new studies are still needed to evaluate the degree of implementation of these guidelines in clinical practice and their consequences on incidence and prognosis of IE. Aim This study ai...

The eukaryotic 60 S-ribosomal stalk consists of P0, P1, and P2 proteins, which associate in a pentameric structure (P1(2)-P0-P2(2)). The Plasmodium falciparum protein P2 (PfP2) appears to play nonribosomal roles. It gets exported to the infected erythrocyte (IE) surface at 30 h post-merozoite invasion (PMI), concomitant with extensive oligomerization. Here we present certain biophysical propert...