The onset of human cytomegalovirus (HCMV) lytic infection is strictly synchronized with the host cell cycle. Infected G0/G1 cells support viral immediate early (IE) gene expression and proceed to the G1/S boundary where they finally arrest. In contrast, S/G2 cells can be infected but effectively block IE gene expression and this inhibition is not relieved until host cells have divided and reent...

Introduction This study assessed the long-term outcomes of patients with chest pain (CP) who had attended a Rapid Access Chest Pain Clinic (RACPC) and were by Dobutamine Stress Echocardiography (DSE). Patients in RACPC are now recommended to under cardiac CT first ischaemia testing reserved for those atypical symptoms coronary disease on CTCA or uncertainty about clinical significance ...

In this short note we observe that the Peikert-Vaikuntanathan-Waters (PVW) method of packing many plaintext elements in a single Regev-type ciphertext, can be used for performing SIMD homomorphic operations on packed ciphertext. This provides an alternative to the Smart-Vercauteren (SV) ciphertextpacking technique that relies on polynomial-CRT. While the SV technique is only applicable to schem...

Theory and research from the marketing literature on customer-based brand equity were used to predict how positive exposure to 4 early recruitment-related activities-publicity, sponsorships, word-of-mouth endorsements, and advertising-may affect the application decisions of engineering students. Similar to prior marketing findings, the results suggested that early recruitment-related activities...

BACKGROUND We sought to summarize and critically appraise the literature on the epidemiology of infective endocarditis (IE) in the general population. METHODS We retrieved population-based IE surveys by searching MEDLINE and EMBASE. Two reviewers independently extracted relevant data. We performed a metaregression to determine if temporal trends of IE characteristics exist. RESULTS Fifteen ...

Infective endocarditis (IE) is a rare disease that is difficult to diagnose, its treatment is complex and expensive, and mortality is high (around 20%). In the field of IE, the most recent changes are epidemiological and include an increased number of cases of IE in patients with prosthetic valves and intracardiac devices and in the population receiving health care, an increased number of cases...

BACKGROUND AND PURPOSE Cerebral ischemic events are highly prevalent and associated with high rates of death and disability in patients with infective endocarditis (IE). However, the role of thrombolysis in these patients remains unclear. We sought to determine the rates and outcomes of acute ischemic stroke patients with IE treated with intravenous thrombolysis (IVT). METHODS We determined t...