The family of 14-3-3 proteins has emerged as critical regulators of diverse cellular responses under both physiological and pathological conditions. To gain insight into the molecular action of 14-3-3ζ in multiple myeloma (MM), we performed a systematic proteomic analysis of 14-3-3ζ-associated proteins. This analysis, recently developed by Matthias Mann, termed quantitative immunoprecipitation ...

The requirements of Instrument Transformers are given in standards IS16227-1, IEC 61869-1 and IEEE Std. C57.13.5. Indian Standard IS 16227-1 is line with 61869-1. Most the utilities India following IS: 16227-1/IEC 61869- 1. Many failures high voltage instrument transformers being reported by utilities. In this connection, a review requirements/test procedure acceptance criteria specified Std C5...

BACKGROUND & AIMS Total parenteral nutrition (TPN), a crucial treatment for patients who cannot receive enteral nutrition, is associated with mucosal atrophy, barrier dysfunction, and infectious complications. Glucagon-like peptide-2 (GLP-2) and epidermal growth factor (EGF) improve intestinal epithelial cell (IEC) responses and attenuate mucosal atrophy in several TPN models. However, it remai...

This article deals with the implementation of P-Class PMU compliant IEC/IEEE Standard 60255-118-1:2018 by usage a multiple-resonator (MR)-based approach for harmonic analysis having been proposed recently. In previously published articles, it has shown that trade-off between opposite requirements is possible shifting measurement time stamp along filter window. Positioning in proximity window ce...

This paper evaluates the Total Vector Error of an estimated Phasor as define in IEEE C37.118 standard within different medium access in Local Area Networks (LAN). Three different LAN models (CSMA/CD, CSMA/AMP and Switched Ethernet) are evaluated. The Total Vector Error of the estimated Phasor has been evaluated for the effect of Nodes Number under the standardized network Band-width values defi...

T he H.264/MPEG-4 Advanced Video Coding standard (H.264/AVC) is the newest video coding standard jointly developed by the ITU-T Video Coding Experts Group (VCEG) and the ISO/IEC Moving Picture Experts Group (MPEG). H.264/AVC has achieved a significant improvement in compression performance compared to prior standards, and it provides a network-friendly representation of the video that addresses...

This paper describes some experiences gained from applying ISO/IEC 15504 for software process assessments focusing on process improvement in four small software companies in Brazil. The assessments have been realized in the context of the research project 15504MPE, which aims at the development of a customized assessment method based on the standard ISO/IEC 15504 adapted to small brazilian soft...

Targeted gene disruption studies have established that the c-Jun NH2-terminal kinase (JNK) is required for the stress-induced release of mitochondrial cytochrome c and apoptosis, and that the Bax subfamily of Bcl-2-related proteins is essential for JNK-dependent apoptosis. However, the mechanism by which JNK regulates Bax has remained unsolved. Here we demonstrate that activated JNK promotes Ba...

14-3-3 proteins were originally discovered as a family of proteins that are highly expressed in the brain. Through interactions with a multitude of binding partners, 14-3-3 proteins impact many aspects of brain function including neural signaling, neuronal development and neuroprotection. Although much remains to be learned and understood, 14-3-3 proteins have been implicated in a variety of ne...