نتایج جستجو برای: il 8

تعداد نتایج: 774060  

2011
Henning W. Zimmermann Sebastian Seidler Nikolaus Gassler Jacob Nattermann Tom Luedde Christian Trautwein Frank Tacke

BACKGROUND Interleukin-8 (IL-8, CXCL8) is a potent chemoattractant for neutrophils and contributes to acute liver inflammation. Much less is known about IL-8 in chronic liver diseases (CLD), but elevated levels were reported from alcoholic and hepatitis C-related CLD. We investigated the regulation of IL-8, its receptors CXCR1 and CXCR2 and possible IL-8 responding cells in CLD patients. METH...

Journal: :Investigative ophthalmology & visual science 2001
A Yoshida S G Elner Z M Bian S L Kunkel N W Lukacs V M Elner

PURPOSE To determine the effects of the potent anti-inflammatory Th2 cytokines, interleukin (IL)-4, -10, and -13, on IL-8 and monocyte chemoattractant protein (MCP) 1 production by human retinal pigment epithelial (HRPE) cells, monocytes, and HRPE cell-monocyte cocultures. METHODS Enzyme-linked immunosorbent assays were performed to determine IL-8 and MCP-1 secretion by HRPE cells, monocytes,...

Journal: :Blood 1993
G W Takahashi D F Andrews M B Lilly J W Singer M R Alderson

Interleukin-8 (IL-8) is a major neutrophil chemoattractant and functional stimulant that is induced by IL-1, tumor necrosis factor alpha (TNF alpha), and lipopolysaccharide (LPS). We report that recombinant human (rh) granulocyte-macrophage colony-stimulating factor (GM-CSF) and rhIL-3 are also potent inducers of IL-8 messenger RNA (mRNA) accumulation and protein secretion by normal peripheral ...

2000
Peng Wang Ping Wu

In highly purified human polymorphonuclear leukocyte (PMN) preparations containing less than 0.1% contaminating monocytes, significant amounts of interleukin-8 (IL-8) and small amounts of IL-la, IL-la, and tumor necrosis factoralpha (TNF-a) were produced by lipopolysaccharide (LPS) stimulation. Contrary to published reports, IL-6 production could not be detected. IL-10 inhibited the produc...

Journal: :iranian journal of allergy, asthma and immunology 0
hui xu department of clinical laboratory, children’s hospital of zhejiang university, school of medicine, hangzhou, pr china yan-xiang pan department of clinical laboratory, children’s hospital of zhejiang university, school of medicine, hangzhou, pr china junfeng zhang department of clinical laboratory, children’s hospital of zhejiang university, school of medicine, hangzhou, pr china yujie liu department of clinical laboratory, children’s hospital of zhejiang university, school of medicine, hangzhou, pr china jian-hua mao department of nephrology, children’s hospital of zhejiang university, school of medicine, hangzhou, pr china wei li department of clinical laboratory, children’s hospital of zhejiang university, school of medicine, hangzhou, pr china

henoch–schönlein purpura (hsp), a common allergic hemorrhagic disease, occurs frequently in children affecting kidney, joint and skin. while interleukin-8 (il-8) plays an important role in inflammation, the association between il-8 gene +781 c/t polymorphism and hsp remains unclear. interleukin-8, an important chemokine related to the initiation and amplification of acute inflammatory responses...

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