BACKGROUND The schistosomiasis affects 200 million people in 70 countries worldwide. It is estimated that 10% of those infected will develop hepatosplenic status and of these, 30% will progress to portal hypertension and esophagogastric varices, whose expression is through gastrointestinal bleeding with significant mortality in the first bleeding episode. Multiple surgical techniques have been ...

P ORTAL-SYSTEMIC SHUNTS HAVE LONG been considered the operation of choice for bleeding from esophageal varices associated with portal hypertension, although impossible or inadvisable in many patients. It may be impossible because there is no suitable patent vein in the portal circulation to anastomose to a systemic vein, or inadvisable because the liver function is too seriously impaired for th...

BACKGROUND AND AIMS Our aim was to evaluate the utility of endoscopic obliterative therapy with Histoacryl for gastric varices and to investigate the incidence of serious complications. METHODS Endoscopic obliterative therapy with Histoacryl was performed on 129 gastric variceal patients. Sixty-five patients had cardiofornical varices, and 64 had fundal varices. Forty-five of 129 patients wer...

Bleeding from ectopic varices is often massive and fatal with portal hypertension, and stomal varices can occur in patients with stoma. We aimed to treat a hepatitis B surface antigen positive 69 year-old male with liver cirrhosis associated hepatocellular carcinoma with bleeding stomal varices using percutaneous injection sclerotherapy. Percutaneous injection sclerotherapy was performed under ...

A 60-year-old man presented with hematemesis. He had been diagnosed with pancreatic tail cancer and gastric varices due to sinistral portal hypertension, which had been observed on computed tomography (CT). An upper gastrointestinal endoscopy was undertaken to assess the gastric varices, and a recent gastric variceal bleed was suggested (Figure 1). Although splenectomy was a definitive therapy,...

Bleeding gastroesophageal varices is associated with a high morbidity and mortality. Forty-four cases of bleeding gastroesophageal varices were treated at the Department of Surgery, Universiti Kebangsaan Malaysia, General Hospital, Kuala Lumpur over four and a half years. Thirty-two of them had liver cirrhosis. Hepatitis B infection was noted in 13 and alcoholic abuse was present in 14 patients...

Gastric variceal bleeding is a major complication of portal hypertension and is associated with high morbidity and mortality. While esophageal varices are more common, gastric varices are often more challenging to treat. Balloon-Occluded Retrograde Transvenous Obliteration is an interventional procedure whereby the portosystemic gastrorenal shunt is accessed via the left renal vein and the gast...

Bleeding from oesophageal varices, oesophageal ulcers or oesophagitis is occasionally massive and difficult to control. Octreotide, a synthetic analogue of somatostin lowers portal pressure and collateral blood flow including that through varices, increases lower oesophageal sphincter pressure, and inhibits the gastric secretion of acid as well as pepsin. Our current experience suggests it is e...

OBJECTIVE To evaluate platelet count/ splenic size ratio as a non-invasive parameter to predict the presence and absence of esophageal varices in patients with cirrhosis of liver. DESIGN An observational, cross- sectional study. PLACE AND DURATION OF STUDY The medical units of the Civil Hospital, Karachi, between October 2003 and October 2004. PATIENTS AND METHODS During one year of study...

OBJECTIVES/HYPOTHESIS To establish risk of hemorrhage in patients with varices compared to those without, determine additional risk factors, and make evidence-based treatment recommendations. STUDY DESIGN Retrospective cohort study. METHODS Patients who were vocal performers presenting for care during a 24-month period were analyzed to determine incidence of hemorrhage. Patients with varice...