Erratum to " Immunoglobulin VH Chain Gene Analysis of Peripheral Blood IgM-Producing B Cells in Patients with Kawasaki Disease " by Lee HH, et al.

The nuclear enzyme terminal deoxynucleotidyl transferase (TdT) is thought to contribute to the diversity of certain immunoglobulin and T cell receptor gene rearrangements through the addition of random nucleotides at their vanable (V)-joining (J) region junctions. An acute lymphoblastic leukemia (ALL) with an immature T cell phenotype (CD7 , CD5 , CD1t CD22, CD3. CD4, CD8 ) was found to be TdT ...

In chronic lymphocytic leukemia, usually a monoclonal disease, multiple productive immunoglobulin heavy chain gene rearrangements are identified sporadically. Prognostication of such cases based on immunoglobulin heavy variable gene mutational status can be problematic, especially if the different rearrangements have discordant mutational status. To gain insight into the possible biological mec...

The aim of the current research was to investigate the effect of aluminum exposure on humoral immunity (immunoglobulin G and immunoglobulin M serum levels), function enzymes, and histological alterations in the liver of rats. Materials & Methods: Sixteen albino male rats at fifteen weeks were grouped into four groups, and administered with aluminum chloride at 35g/Kg of body weight for 8, 12 ...

X-linked agammaglobulinemia (XLA), or Bruton’s agammaglobulinemia, – is a primary immunodeficiency, caused by defects in the BTK gene encoding tyrosine kinase. The lead to arrest of B-lymphocyte development and, as result, agammaglobulinemia. disease manifests with recurrent infections starting infancy. gold standard XLA treatment intravenous subcutaneous immunoglobulin substitution proved effe...

purpose the aim of this study was to compare the levels of serum immunoglobulin (iga, igm, igg), testosterone and cortisol in semi-endurance elite runners during general preparation and competition phase of training. methods thirteen semi-endurance elite male runners with an average age of 18.92±1.7 years volunteered to take part in this study. the runners participated in the selected training ...

Agglutinin responses to sheep erythrocytes and immunoglobulin heavy chain phenotypes determined in F(1), F(2), and backcross progeny of mice genetically selected for high and low antibody synthesis indicated that an immune response gene for sheep erythrocytes is linked to the immunoglobulin heavy chain allotype. Mice homozygous for the phenotype of the high line had significantly higher titers ...

Antigen-specific factors associated with immunosuppressive activity, released by cultured T cells from mice tolerant to the haptens trinitrophenyl, dinitrophenyl and oxazolone, were purified by hapten affinity chromatography. Their binding specificity for antigens paralleled their immunoregulatory activity. Like some immunoglobulin molecules, these factors had blocked NH2 termini and could be b...