نتایج جستجو برای: in situ cross

تعداد نتایج: 17044010  

ژورنال: :مجله دانشگاه علوم پزشکی مازندران 0
جعفر اکبری jafar akbari associate professor, department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences, sari, iranدانشیار، گروه فارماسیوتیکس، دانشکده داروسازی، دانشگاه علوم پزشکی مازندران، ساری، ایران رضا عنایتی فرد reza enayatifard associate professor, department of pharmaceutics, faculty of pharmacy, mazandaran university of medical sciences, sari, iranساری: کیلومتر 18 جاده خزر آباد، مجتمع دانشگاهی پیامبر اعظم، دانشکده داروسازی مجید سعیدی majid saeedi professor, department of pharmaceutics, pharmaceutical sciences research center, faculty of pharmacy, mazandaran university of medical sciences, sari, iranاستاد، مرکز تحقیقات علوم دارویی، دانشکده داروسازی، دانشگاه علوم پزشکی مازندران، ساری، ایران لاله کلوی laleh kalavi pharmacy students, student research committee, faculty of pharmacy, mazandaran university of medical sciences, sari, iranدانشجوی داروسازی،کمیته تحقیقات داشجویی، دانشکده داروسازی، دانشگاه علوم پزشکی مازندران، ساری، ایران

سابقه و هدف: در روند آزاد سازی داروها به صورت چشمی، محدودیت های فیزیولوژیک ایجاد شده توسط مکانیسم های حفاظتی چشم، منجر به جذب کم داروها شده و مدت زمان تاثیر درمانی کاهش می یابد. بنابراین با استفاده از سیستم های ژل شونده در محل، زمان ماندگاری دارو در چشم افزایش خواهد داشت. این سیستم ها به صورت قطره داخل چشم ریخته شده و در حفره چشمی از حالت سل به ژل تبدیل می شوند. از این رو هدف از مطالعه حاضر، فر...

Journal: :journal of lasers in medical sciences 0
ali mostafaie iranian center for evidence based medicine, tabriz university of medical sciences, tabriz, iran alireza mahboub ahari tehran university of medical sciences, tehran, iran fatemeh sadeghi ghyassi iranian center for evidence based medicine, tabriz university of medical sciences, tabriz, iran sakineh hajebrahimi iranian center for evidence based medicine, tabriz university of medical sciences, tabriz, iran mahmoud yousefi tehran university of medical sciences, tehran, iran

introduction: to compare the efficacy and cost-effectiveness of femtosecond laser versus mechanical microkeratome corneal flap creation in correction of refractive errors. methods: i this review, a comprehensive search of medline, scopus, cochrane, trip database, supplemented by hta and economic databases was performed. we searched for randomized controlled trials (rcts) of femtosecond laser wh...

Journal: :iranian journal of chemistry and chemical engineering (ijcce) 2012
akram kazemzadeh behruz bayati neda kalantari ali akbar babaluo

polycrystalline mfi zeolite membranes were prepared on α-alumina tubular support by hydrothermal treatments at 413 k. the synthesized zeolite membranes were characterized by xrd, sem and single gas permeation. the influence of hydrothermal treatment steps and the calcination time on the zeolite layer formation were investigated. mfi zeolite membrane prepared by four subsequent hydrothermal trea...

Journal: :geopersia 0
hamid sharifi galiuk institute of petroleum industry, tehran hessam aloki bakhtiari institute of petroleum industry, tehran rezvan behin institute of petroleum industry, tehran mohammad reza esfahani institute of petroleum industry, tehran

the simultaneous flow of oil and water in porous media is described by relative permeability curves, mainly derived from laboratory experiments. relative permeability is of paramount importance in predicting reservoir production performance and drive mechanisms and its value depends largely on the volume fraction of fluids present in the test samples. nowadays x-ray scanners are one of the most...

Journal: :iranian journal of pharmaceutical sciences 0
golnar dorraj department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, po box: 14155-6153, tehran, iran. hamid r. moghimi department of pharmaceutics and nanotechnology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. pharmaceutical sciences research center, shahid beheshti university of medical sciences, tehran, iran.

preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of nile red-loaded solid lipid nanoparticles. nanoparticles (nps) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. to solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

2010
A. Matrone Rebecca A. Whipple Eric M. Balzer Stuart S. Martin

nloaded ection of circulating tumor cells (CTC) is advancing as an effective predictor of patient outcome and eutic response. Unfortunately, our knowledge of CTC biology remains limited, and the impact of treatments on CTC metastatic potential is currently unclear. Improved CTC imaging in vivo and is of free-floating tumor cells now show that cytoskeletal regulation in CTCs contrasts starkly wi...

2015
Stephanie L. Daifuku Jared L. Kneebone Benjamin E. R. Snyder Michael L. Neidig

While previous studies have identified FeMes2(SciOPP) as the active catalyst species in iron-SciOPP catalyzed Kumada cross-coupling of mesitylmagnesium bromide and primary alkyl halides, the active catalyst species in cross-couplings with phenyl nucleophiles, where low valent iron species might be prevalent due to accessible reductive elimination pathways, remains undefined. In the present stud...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه اصفهان - دانشکده زبانهای خارجی 1391

چکیده حیطه ی نوشتار دانشگاهی اخیرا شاهد تغییرات عمده ای از غیرشخصی بودن (عینی بودن) به شخصی بودن بوده است. شخصی بودن متون دانشگاهی اهمیت استفاده از وجهیت معرفتی را برجسته می سازد چرا که? وجهیت معرفتی? بر اساس یکی از تعاریف ارائه شده از این مقوله? ارتباط تنگاتنگی با شخصی بودن داشته و به عنوان بیان نظر شخصی گوینده در مورد جز گزاره ای گفته در نظر گرفته میشود. بنابراین? با در نظر داشتن نقاط مشترک...

Journal: :Molecular bioSystems 2014
Peng Xie Yu Liu Yanda Li Michael Q Zhang Xiaowo Wang

MicroRNA (miRNA) regulation is highly cell-type specific. It is sensitive to both the miRNA-mRNA relative abundance and the competitive endogenous RNA (ceRNA) effect. However, almost all existing miRNA target prediction methods neglected the influence of the cellular environment when analyzing miRNA regulation effects. In this study, we proposed a method, MIROR (miRNA Occupancy Rate predictor),...

2017
Yoichiro Yamamoto Akira Saito Ayako Tateishi Hisashi Shimojo Hiroyuki Kanno Shinichi Tsuchiya Ken-ichi Ito Eric Cosatto Hans Peter Graf Rodrigo R. Moraleda Roland Eils Niels Grabe

Machine learning systems have recently received increased attention for their broad applications in several fields. In this study, we show for the first time that histological types of breast tumors can be classified using subtle morphological differences of microenvironmental myoepithelial cell nuclei without any direct information about neoplastic tumor cells. We quantitatively measured 11661...

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