Objective of the present study is to investigate the effect of coated edible films with chitosan solutions enriched with essential oil (EO) on the chemical, microbial and sensory properties of Kashar cheese during ripening time. Generally, no differences were found in total aerobic mesophilic bacteria, streptococci and lactoccocci counts among cheeses but these microorganism counts increased du...

A flow microdevice with programmable in situ formation/dissolution of a hydrogel 3D network was designed. An active porous medium shows excellent bio-compatibility and promises high, long-term activities without leaching immobilized biomolecules.

In order to mimic the natural cartilage extracellular matrix, which is composed of core proteins and glycosaminoglycans, a biological hydrogel was synthesized from the biopolymers hyaluronic acid (HA), chondroitin sulfate (CS) and gelatin via click chemistry. HA and CS were modified with 11-azido-3,6,9-trioxaundecan-1-amine (AA) and gelatin was modified with propiolic acid (PA). The molecular s...

Wharton’s jelly mesenchymal stem cells (HWJMSCs) hold promise for myocardial regeneration, but optimal treatment regimen (preferably with a growth factor) is required to maximize functional benefits. The aim of this study was to explore the cardioprotective and angiogenesis effects of HWJMSCs combined with insulin-like growth factor-1 (IGF-1) in the treatment of acute myocardial infarction. Th...

The objective of this study was to evaluate the pharmacokinetic characteristics of enrofloxacin (ENR) in situ forming gel in pigs following a single intramuscular administration. Twelve healthy pigs were randomly divided into two groups (6 pigs per group), then administered 20 mg/kg body weight (b.w.) ENR in situ forming gel and 5 mg/kg b.w. ENR conventional injection respectively. Highperforma...

Four derivatives of hyaluronic acid (HA) bearing thiol (HA-SH), hydrazide (HA-hy), 2-dithiopyridyl (HA-SSPy), and aldehyde groups (HA-al) respectively were synthesized. Thiol and 2-dithiopyridyl as well as hydrazide and aldehyde make up two chemically orthogonal pairs of chemo-selective functionalities that allow in situ formation of interpenetrating (IPN) disulfide and hydrazone networks simul...

Non-viral gene delivery holds great promise for promoting tissue regeneration, and offers a potentially safer alternative than viral vectors. Great progress has been made to develop biodegradable polymeric vectors for non-viral gene delivery in 2D culture, which generally involves isolating and modifying cells in vitro, followed by subsequent transplantation in vivo. Scaffold-mediated gene deli...

Ulvan is a natural sulfated polysaccharide obtained from marine green algae composed of 3-sulfated rhamnoglucuronan as the main component. It has unique chemical structure that rich L-rhamnosa, D-glucuronic acid, and L-iduronic acid. similar to glycosaminoglycans (GAGs) in mammals including chondroitin sulfate, dermatan heparan sulfate broad range applications for many years. Here, we provide a...