1. The minimum dose of x-ray, of each of three degrees of hardness, required to produce persistent alopecia of the abdominal skin of normal white rabbits has been studied. 40 kilovolt rays filtered by 0.5 mm., 50 kilovolt rays filtered by 1 mm., and 70 kilovolt rays filtered by 1.5 mm. of aluminium were employed. The 70 kilovolt work is unfinished. 2. Under constant conditions of treatment, the...

The pharmacokinetics of piperacillin were examined after single intravenous doses to three groups of male patients with creatinine clearances of greater than or equal to 60 (group I), greater than or equal to 20 but less than 60 (group II), and less than 20 (group III) ml/min per 1.73 m2. Each of 32 patients received either 1 or 4 g of piperacillin as a bolus injection. Three patients received ...

Procalcitonin (PCT) has been shown to be a useful surrogate marker in identifying patients with various bacterial infections. PCT has been studied as a diagnostic marker in differentiating bacterial pneumonia from other respiratory conditions such as chronic obstructive pulmonary disease exacerbations or viral pneumonia. Differentiating bacterial from nonbacterial pneumonia using PCT has shown ...

OBJECTIVE To compare pharmacokinetics and clearances of creatinine and iohexol as estimates of glomerular filtration rate (GFR) in dogs with various degrees of renal function. ANIMALS 50 Great Anglo-Francais Tricolor Hounds with various degrees of renal function. PROCEDURES Boluses of iohexol (40 mg/kg) and creatinine (647 mg/kg) were injected IV. Blood samples were collected before adminis...

Severe myocardial necrosis was produced in virgin Sprague-Dawley rats without preexisting arteriosclerosis and in breeder Sprague-Dawley rats with various degrees of arteriosclerosis by giving two subcutaneous injections of isoproterenol; the virgin rats received 50 mg/100 g and the breeder rats 25 mg/100 g body weight. Breeder rats withstood the stress and shock of myocardial necrosis with few...

This 16-week study evaluated pharmacokinetics and pharmacodynamics of denosumab in 55 subjects with renal function ranging from normal to dialysis-dependent kidney failure. Participants received a single 60-mg subcutaneous dose of denosumab. Kidney function groups were based on calculations using the Cockcroft-Gault equation and U.S. Food and Drug Administration (FDA) guidance in place when the...

vinca minor, vinca major, vinca variegata and vinca rosea are different species of vinca genus, of apocynaceae family. in addition to ornamental applications, they are placed in the group of medicinal plants , because of the various alkaloids they possess. the purpose of this research was the investigation of the antileishmanial effects of the methanolic and crude extracts of leaves and stems o...

Effects of individual differences in working memory on performance and trust with various degrees of automation Ericka Rovira, Richard Pak & Anne McLaughlin To cite this article: Ericka Rovira, Richard Pak & Anne McLaughlin (2016): Effects of individual differences in working memory on performance and trust with various degrees of automation, Theoretical Issues in Ergonomics Science, DOI: 10.10...

The pharmacokinetic profile of recombinant human erythropoietin (rHuEpo) was studied after a single intravenous dose of 150 U/kg in ten patients with various degrees of renal function: group I, creatinine clearance greater than 80 ml/min, n = 2; group II, creatinine clearance 10-50 ml/min, n = 6; group III, creatinine clearance less than 3 ml/min (patients undergoing haemodialysis) n = 2. Eryth...

BACKGROUND Several lengthening techniques have been proposed for upper eyelid retraction in patients with Graves' orbitopathy and variable rates of success have been reported. Most authors recommend different procedures for different degrees of retraction, but cannot prevent residual temporal retraction in a significant number of cases. The modified levator aponeurosis recession described by Ha...