نتایج جستجو برای: inactivating

تعداد نتایج: 7091  

Journal: :Anesthesiology 2000
A Olschewski M E Bräu G Hempelmann W Vogel B V Safronov

BACKGROUND Dorsal horn neurons of the spinal cord participate in neuronal pain transmission. During spinal and epidural anesthesia, dorsal horn neurons are exposed to local anesthetics and opioids. Droperidol is usually given with opioids to avoid nausea and vomiting. A recently developed method of "entire soma isolation" has made it possible to study directly the action of droperidol on differ...

Journal: :Journal of clinical microbiology 1976
O P Larghi V L Savy A E Nebel A Rodriguez

The replication of seven rabies virus strains (CVS, HEP, PV, ERA, WIRAB, CPZ and BOLIVAR) in BHK cells and the inactivation dynamics of these strains by beta-propiolactone, acetylethylenimine, and ethylenimine were studied to find the most immunogenic strain and the most economic and stable inactivating agent for the production of an inactivated tissue culture rabies vaccine for animal use. The...

Journal: :Carcinogenesis 1997
S J London A K Daly J B Leathart W C Navidi C C Carpenter J R Idle

The well described genetic polymorphism of the CYP2D6 gene influences response to a wide variety of therapeutic agents metabolized by the CYP2D6 enzyme product. CYP2D6 also appears to play a role, along with other cytochrome P450 enzymes, in the metabolic activation of the tobacco specific nitrosamine, NNK, as well as metabolism of nicotine to cotinine. While impaired activity of CYP2D6 was str...

Journal: :Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 1965

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