background glioblastoma is a type of brain tumor with poor response to available therapies, and shows high rate of mortality. despite remarkable advancements in our knowledge about cytogenetic and pathophysiologic features of glioblastoma, current treatment strategies are mainly based on cytotoxic drugs; however, these therapeutic approaches are facing progressive failure because of the resista...

the potential of marine actinobacteria particularly streptomyces as a single cell protein (scp) feed for the growth of ornamental fish, xiphophorus helleri has been investigated. the streptomyces strains used as scp were isolated from the marine sponges, namely callyspongia diffusa , mycale mytilorum , tedania anhelans and dysidea fragilis . six scp feeds were prepared and their effects were co...

In a 1994 Medical Hypotheses paper, it was speculated that high intracranial pressure (ICP) might increase the probability of developing Alzheimer's disease (AD). A study of cerebrospinal fluid pressure (CSFP) in normal volunteers showed interindividual variations in CSFP. Some normals had what would normally be considered elevated CSFP. The hypothesis postulated that this subgroup with a high ...

Hepatitis C virus (HCV)-mediated liver disease progression may reflect distinct molecular mechanisms for increased hepatocyte growth and hepatic stellate cell activation. In this study, we have observed that primary human hepatocytes, when infected in vitro with cell culture-grown HCV genotype 1a or 2a, display viral RNA and protein expression. Infected hepatocytes displayed a fibroblast-like s...

The witches’ broom disease of lime trees is a destructing disease caused by the bacterium Candidatus <span style="font-variant: normal; fon...

Nafion-coated bismuth film electrodes (NCBFEs) and Nafion-coated mercury film electrodes (NCMFEs) were used to electrochemically preconcentrate metal analytes for subsequent analysis by inductively coupled plasma-mass spectrometry (ICP-MS). Either type of electrodes is part of a thin-layer electrochemical flow cell that is positioned upstream of a microconcentric nebulizer for the ICP-MS. Perfo...

conclusions taken together, these data reveal that cellular protease of chicken liver cells allows the replication of high yields of h9n2 virus in the absence of trypsin and also cell death in the infected cells is due to necrosis. results the degree of viability was significantly reduced in infected hepatoma cells. observations of caspase activation and cell dna laddering in infected cells wer...

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has become established as a very efficient and sensitive trace, ultratrace, and surface analytical technique in the life sciences. We have developed a new analytical imaging technique using LA-ICP-MS to study element distribution in biological tissues. Nowadays, imaging LA-ICPMS using double-focusing sector field (LA-ICP-SF...

background: the aim of the present study was to investigate the immunomodulation effects of aqueous garlic extract (age) in the cultured macrophages infected by leishmania major . methods: after j774 macrophages proliferation in rpmi1640 and incubation with leishmania for 72 hours, age was added in doses of 9.25, 18.5, 37, 74 and 148 mg/ml for 18, 24 and 48 hours and cell culture supernatants w...

UNLABELLED Infection with adenovirus triggers the cellular DNA damage response, elements of which include cell death and cell cycle arrest. Early adenoviral proteins, including the E1B-55K and E4orf3 proteins, inhibit signaling in response to DNA damage. A fraction of cells infected with an adenovirus mutant unable to express the E1B-55K and E4orf3 genes appeared to arrest in a mitotic-like sta...