In this essay we advance the view that analytical epistemology and artificial intelligence are complementary disciplines. Both fields study epistemic relations, but whereas artificial intelligence approaches this subject from the perspective of understanding formal and computational properties of frameworks purporting to model some epistemic relation or other, traditional epistemology approache...

Two multivariable inferential feed-forward control strategies are proposed in this paper. In the first strategy, the effects of disturbances on the primary process variables are inferred from uncontrolled secondary process variables that are measured on-line. In the second approach, the effects of disturbances on the primary process variables are inferred from the manipulated variables for thos...

In this tutorial, we discuss approaches to control of one or more primary variables in a process using secondary measurements. This approach is useful when the primary variable is not easily measured, or has large time delays or lags associated with it. It is also useful when the secondary measurements contain information about disturbances that affect the primary variable. We start by discussi...

We distinguish between, and discuss the applicability of, two levels of rigidity in rigid-body collision modeling. For rigidity in the strong, force-response, sense collisional contact deformations must be highly localized. The bodies then move according to second order rigid-body mechanics during the collision. Incremental collision laws and most collision models using continuum mechanics for ...

Flexibility-rigidity index (FRI) has been developed as a robust, accurate, and efficient method for macromolecular thermal fluctuation analysis and B-factor prediction. The performance of FRI depends on its formulations of rigidity index and flexibility index. In this work, we introduce alternative rigidity and flexibility formulations. The structure of the classic Gaussian surface is utilized ...

PURPOSE To determine whether variation in ocular rigidity (a quantity that describes the elastic properties of the globe) affects the characteristics of horizontal saccadic eye movements. METHODS Thirty-three young, visually healthy subjects participated with informed consent in the study. Axial length was measured using the IOLMaster ocular biometer. Ocular rigidity coefficients were determi...

We study the generic rigidity properties of systems of volume constraints. We formally define, in an algebraic geometrical setting, the volume rigidity problem and extract its underlying sparse hypergraph structure. Then we develop a combinatorial theory of cocircuit matroids which leads to a very general linear representation result for sparse hypergraphs. Applying this to the volume rigidity ...

PURPOSE To measure the rigidity coefficient of a large number of subjects at clinically encountered intraocular pressures (IOPs) and to examine the possible correlation of ocular rigidity with other factors, such as the age of the patients, ocular parameters (axial length and corneal thickness), and pathologic conditions affecting the eye. METHODS The pressure-volume relationship and the ocul...

In this study, we established that collagen gel, but not collagen gel coating, induced apoptosis exclusively in epithelial cell lines, which indicated that low substratum rigidity might trigger cell apoptosis. To confirm this, we used collagen gels with different rigidities due to cross-linking or physical disruption of collagen fibrils caused by sonication. We found that collagen gel-induced a...