Vagus nerve stimulation (VNS) is a technology that provides electrical to the cervical vagus and can be applied in treatment of wide variety neuropsychiatric systemic diseases. VNS exerts its effect by stimulating vagal afferent efferent fibers, which project upward brainstem nuclei relayed circuits downward internal organs influence autonomic, neuroendocrine, neuroimmunology systems. The neuro...

Naproxen (NAP) is an aromatic propionic acid nonsteroidal anti-inflammatory drug, and vortioxetine (VOT) a novel antidepressant drug. In this study, new 1 : drug-drug salt of NAP VOT (namely, NAP-VOT) was designed synthesized by liquid-assisted grinding slow evaporation. The obtained characterized single-crystal X-ray diffraction, powder diffraction (PXRD), differential scanning calorimetry (DS...

There is histological evidence that drug-eluting stents are associated with delayed endothelialization and a persistent inflammatory state. Moreover, clusters of inflammatory cells have been observed on luminal surfaces by scanning electron microscopy. With the aim of quantifying this inflammatory response, we implanted one bare-metal stent and two drug-eluting stents containing different doses...

Canarium L. is used in folk medicine as anti-inflammatory, antibacterial, antifungal, antitumor, heptoprotective, antioxidant, and anti diabetic properties. The present study investigeated the invivo anti-inflammatory activity of  essential oil obtained by hydrodistillation of resin of Canarium strictum Roxb. In the current study, anti-inflammatory activity of essential oil of...

OBJECTIVES This study examined periarticular multimodal drug injection and the use of nonsteroidal anti-inflammatory drugs for an early analgesic effect after total knee arthroplasty and total hip arthroplasty. Patient satisfaction and benefits from the treatment were also assessed. METHODS A total of 110 patients who were scheduled to undergo total knee arthroplasty and 86 patients who were ...

The purpose of the present study was to investigate the anti-inflammatory properties of ethanolic extract of the leaves of Holoptelea integrifolia Planch. (EHI). The different anti-inflammatory models were used. The EHI at dose (250 and 500mg/kg p.o) was given to observe percentage inhibition of paw oedema which were comparable with indomethacin (10mg/kg p.o) used as a reference drug. The extra...

A series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (C1-C7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. All the synthesis compounds have been characterized by 1HNMR, IR and Mass spectral data. The compounds were purified...

Citation: Vetreno RP, Lawrimore CJ, Rowsey PJ and Crews FT (2018) Persistent Adult Neuroimmune Activation and Loss of Hippocampal Neurogenesis Following Adolescent Ethanol Exposure: Blockade by Exercise and the Anti-inflammatory Drug Indomethacin. Front. Neurosci. 12:200. doi: 10.3389/fnins.2018.00200 Persistent Adult Neuroimmune Activation and Loss of Hippocampal Neurogenesis Following Adolesc...

AbstractFixed drug eruption (FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. FDE is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. A 27-year-old woman presented with multiple dark patches over her eyelids...